6,473 results found
    1. Ecology

    Tree species and genetic diversity increase productivity via functional diversity and trophic feedbacks

    Ting Tang, Naili Zhang ... Xiaojuan Liu
    Species and genetic diversity promote tree community productivity by increasing functional diversity and reducing herbivore damage and soil fungal diversity.
    1. Genetics and Genomics

    Age and diet shape the genetic architecture of body weight in diversity outbred mice

    Kevin M Wright, Andrew G Deighan ... Anil Raj
    Genetic effects on body weight in mice are highly heterogeneous, dynamic, and nonlinear with respect to genomic background, age, and diet.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations

    Tim A Crombie, Stefan Zdraljevic ... Erik C Andersen
    Hawaiian Caenorhabditis elegans harbor high levels of genetic diversity that might represent the complex patterns of ancestral diversity in the species prior to human influence.
    1. Cancer Biology
    2. Cell Biology

    TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

    Debjani Pal, Anja Pertot ... Raffaella Sordella
    Phenotypic diversity and cell state transition (i.e., acquisition of a CD44+/CD24- cell state or exposure to TGF-beta) can spur intra-tumor genetic heterogeneity and contribute to acquired resistance.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Patterns of within-host genetic diversity in SARS-CoV-2

    Gerry Tonkin-Hill, Inigo Martincorena ... Wellcome Sanger Institute COVID-19 Surveillance Team
    Characterisation of within-host diversity of SARS-CoV-2 provides insights into the mutational and selective mechanisms driving its evolution and has important implications for using within-host variation to inform transmission inference efforts.
    1. Ecology
    2. Evolutionary Biology

    Megafaunal extinctions, not climate change, may explain Holocene genetic diversity declines in Numenius shorebirds

    Hui Zhen Tan, Justin JFJ Jansen ... Frank E Rheindt
    Application of museomics facilitates characterization of the contribution of historical factors to genetic diversity declines in Numenius shorebirds and highlights that extinction of ecosystem-engineering megafauna may have been detrimental for open-landscape species.
    1. Evolutionary Biology

    Quantifying the relationship between genetic diversity and population size suggests natural selection cannot explain Lewontin’s Paradox

    Vince Buffalo
    Quantifying the relationship between census sizes and genetic diversity estimates provides insights into whether natural selection can explain the narrow range of diversity between species.
    1. Cancer Biology

    Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer

    Andrea Strakova, Máire Ní Leathlobhair ... Elizabeth P Murchison
    Genetics of a canine transmissible tumour show how the world’s oldest cancer “metastasised” through the global dog population – and captured, maintained and rearranged its mitochondrial DNA along the way.
    1. Genetics and Genomics

    Data-driven, participatory characterization of farmer varieties discloses teff breeding potential under current and future climates

    Aemiro Bezabih Woldeyohannes, Sessen Daniel Iohannes ... Matteo Dell'Acqua
    A genomic, climatic, agronomic, and participatory characterization of teff agrobiodiversity shows opportunities and challenges of teff improvement in the face of climate change.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements

    David A Murphy, Eyal Elyashiv ... Guy Sella
    Background selection is shown to be the dominant mode of linked selection in humans, with marked effects on diversity levels throughout autosomes.

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