13,425 results found
    1. Ecology
    2. Genetics and Genomics

    Individual differences in honey bee behavior enabled by plasticity in brain gene regulatory networks

    Beryl M Jones, Vikyath D Rao ... Gene E Robinson
    Integration of automatic behavioral tracking with brain molecular profiling reveals the role of gene regulatory network plasticity in the regulation of behavioral phenotypes.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon, Sarah E Lower ... Jing-Ke Weng
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Evolutionary Biology

    The rise and fall of the ancient northern pike master sex-determining gene

    Qiaowei Pan, Romain Feron ... Yann Guiguen
    Tracing the evolution of an old master sex determination gene reveals a diversity of sex determination transitions, including a complete Y chromosome loss, among an old teleost order (Esociformes).
    1. Chromosomes and Gene Expression

    Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation

    Ava C Carter, Jin Xu ... Howard Y Chang
    A long noncoding RNA uses viral mimicry to achieve developmental gene silencing across a chromosome.
    1. Genetics and Genomics

    Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells

    Helen M Tauc, Imilce A Rodriguez-Fernandez ... Heinrich Jasper
    Global, multi-angled genetic analyses identified an age-associated loss of stem cell lineage fidelity that was linked to changes in polycomb regulation in the Drosophila intestinal epithelium.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA

    Natasha M O'Brown, Brian R Summers ... David M Kingsley
    An identical DNA base pair change has occurred in divergent sticklebacks to alter the expression of a major developmental gene controlling armor plates, thus providing a molecular link between particular enhancer changes, cell signaling, and repeated skeletal evolution in natural populations.
    1. Microbiology and Infectious Disease

    Targeted genomic sequencing with probe capture for discovery and surveillance of coronaviruses in bats

    Kevin S Kuchinski, Kara D Loos ... Andrew DS Cameron
    Hybridization probe capture is useful for discovery and surveillance of novel coronaviruses, and its unique strengths complement existing methods like amplicon sequencing and deep metagenomic sequencing.
    1. Developmental Biology
    2. Genetics and Genomics

    The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion

    Damian Kao, Alvina G Lai ... Aziz Aboobaker
    The first malacostracan genome sequence will establish the genetically tractable Parhyale hawaiensis as a model organism in this key animal group.
    1. Evolutionary Biology

    The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions

    Alessandro W Rossoni, Dana C Price ... Andreas PM Weber
    Horizontal gene transfer (HGT) analysis in polyextremophile red algae (Cyanidiales) provides explanations for the nonexistence of cumulative effects and eukaryotic pangenomes, and highlights differences between HGT and native genes.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A test of the pioneer factor hypothesis using ectopic liver gene activation

    Jeffrey L Hansen, Kaiser J Loell, Barak A Cohen
    Pioneering activity may be a property of all transcription factors with sufficient affinity for their targets rather than a property of specific classes of transcription factors.

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