Sasha A Langley, Karen H Miga ... Charles H Langley
Genomic polymorphism across centromeric regions of humans is organized into large-scale haplotypes with great diversity, including entire Neanderthal centromeres.
Variation in the rate of mixed infections by malaria parasites and the relatedness structure among infecting strains reveals diversity in local epidemiological processes.
Jonci Nikolai Wolff, Neil J Gemmell ... Damian K Dowling
Mitochondrial genomes harbor male-fertility-reducing mutations that can be harnessed to control population viability as a novel approach to control economic and environmental pests.
Julia M Kreiner, George Sandler ... Stephen I Wright
The spread of herbicide resistance in one of the most problematic weeds in North America occurs through both recent, repeated mutational origins and gene flow across an international network of agricultural fields.
Jo Hepworth, Rea L Antoniou-Kourounioti ... Caroline Dean
Variation in autumnal expression from starting expression levels and initial cold-down-regulation, rather than epigenetic silencing, is the major field variable conferred by worldwide haplotypes of the floral repressor gene, FLC.
Fully functional regulatory elements can arise rapidly from transposable elements via a novel route where non-allelic gene conversion can act to speed up the evolutionary fine-tuning of regulatory elements.
Ulrich Lutz, Thomas Nussbaumer ... Claus Schwechheimer
Gene expression changes associated with polymorphisms in non-coding sequences of the flowering time regulator FLM directly influence flowering time in ambient temperature in Arabidopsis over an extended vegetative period.
Jacob A Tennessen, Stephanie R Bollmann ... Michael Scott Blouin
A region of the Biomphalaria genome, containing highly divergent haplotypes with different combinations of transmembrane genes, strongly impacts whether these snails can transmit parasitic schistosomes.
Paul E Chappell, El Kahina Meziane ... Jim Kaufman
The number of different peptides presented by major histocompatibility complex class I molecules to the immune system's T lymphocytes is inversely correlated with cell surface expression and is strongly associated with the response to infectious disease.