Training enables adult humans to rapidly adapt their sound localization abilities to unilateral hearing loss by combining different strategies that rely on partially distinct neurophysiological substrates.

Short linear motifs throughout the intrinsically disordered proteome use sequence context in diverse ways to target actin remodeler ENAH.

A peptide from PCARE achieves >100-fold binding specificity for the EVH1 domain of ENAH, a protein important for metastasis, using a conformational shift mechanism unavailable to ENAH's closely related paralogs VASP and EVL.

Individual scientists, scientific communities and scientific journals can do more to assess the publication of irreproducible results, to promote good science, and to increase the efficiency with which the scientific community self-corrects.

The synaptic structure in mouse V1 is explained by a synergy of homeostatic plasticity in incoming and outgoing synapses of inhibitory interneurons, establishing a stimulus-specific balance of excitation and inhibition.

A large variety of spatial representations implied in rodent navigation could arise robustly and rapidly from inputs with a weak spatial structure, by an interaction of excitatory and inhibitory synaptic plasticity.

Single-cell transcriptomics of intraocular infiltrate in human HLA-B27-associated active anterior uveitis shows a unique composition and phenotype of leukocytes preferentially affecting dendritic cells.

Diverse photographs of human faces against their natural background trigger a specific electrical response in the right hemisphere of the brain in infants aged 4–6 months.

The formation and refinement of prediction error circuits relies on an experience-dependent balance of excitation and inhibition in canonical microcircuits.

A newly discovered cytoplasmic intermediate filament in water bears may help these animals to resist extreme environmental conditions.