Combined single nucleus RNAseq and ATACseq enabled the first molecular resolution of all hindbrain rhombomeres, the derivation of a unique gene regulatory network for each rhombomere, and the identification of gene expression changes as rhombomeres form from early progenitor pools.

The digital 3D-atlas maker will help ascribing neuronal birthdate and neuronal differentiation times upon gene disruption in zebrafish avatars for human diseases, and will allow the integration of the information generated in other laboratories.

Automated liquid handling, whole mount staining, and clearing allow unbiased 3D quantitation of cell markers in human neural organoids with diameters of up to 1 mm at the single-cell level.

Single nuclei RNA sequencing unmasks 16 variants of midbrain dopamine neurons within a continuum of their gene expression landscape and resolves their differential vulnerability.

Data collected from two important auditory brain areas distinguish effects of generalized arousal and specific task engagement on neural sensory coding.

Regulation of Cav2.3 Ca²⁺ channels by membrane-bound β2 subunit splice variants permits long-lasting channel activity even during prolonged and continuous activity in dopamine neurons, with implications for Parkinson's disease pathophysiology.

Direct measurements of retinoic acid using fluorescence lifetime imaging reveal a new role for cellular retinoic acid binding proteins in noise attenuation that is critical to sharpen hindbrain rhombomere boundaries.

Activity in the midbrain responds to unexpected changes in outcome identity (i.e. sensory prediction error) but does not scale with perceptual distance between expected and receipt reward.

Dopaminergic input shapes activity of specialized amygdala inhibitory cell clusters by ionotropic and metabotropic mechanisms that may enable their selection during distinct fear-related behavioral states.

The molecular mechanisms by which midbrain dopamine neurons acquire the inhibitory neurotransmitter GABA for synaptic release are revealed.