13,147 results found
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Information content differentiates enhancers from silencers in mouse photoreceptors

    Ryan Z Friedman, David M Granas ... Michael A White
    Silencers and enhancers targeted by a common transcription factor in photoreceptors are distinguished by the number and diversity of binding transcription factor binding sites they contain.
    1. Cell Biology
    2. Computational and Systems Biology

    Information transfer in mammalian glycan-based communication

    Felix F Fuchsberger, Dongyoon Kim ... Christoph Rademacher
    The information stored in glycans is interpreted and read by cell surface-exposed lectin receptors, and with information theory, the formal framework is set for how to analyze such complex single-cell data.
    1. Neuroscience

    Humans actively sample evidence to support prior beliefs

    Paula Kaanders, Pradyumna Sepulveda ... Benedetto De Martino
    In a perceptual choice task, human participants have a preference for sampling more information from a previously chosen alternative, indicating the presence of 'confirmation bias' in perceptual decision-making.
    1. Ecology
    2. Physics of Living Systems

    Revealing the structure of information flows discriminates similar animal social behaviors

    Gabriele Valentini, Nobuaki Mizumoto ... Sara I Walker
    Information theory reveals that apparently similar signaling behaviors in ants and termites are instead governed by distinct communication protocols explaining their underlying different functions.
    1. Neuroscience

    Efficient sampling and noisy decisions

    Joseph A Heng, Michael Woodford, Rafael Polania
    An efficient coding theory for higher-level cognitive processes reveals that humans efficiently adapt to contextual distributions by economizing on environmental prior information.
    1. Computational and Systems Biology
    2. Neuroscience

    Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

    Mikko Juusola, An Dau ... Jouni Takalo
    New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
    1. Neuroscience

    Maximally informative foraging by Caenorhabditis elegans

    Adam J Calhoun, Sreekanth H Chalasani, Tatyana O Sharpee
    C. elegans foraging efficiently approximate maximally informative search strategies that involve abrupt switching between different types of behaviors.
    1. Cell Biology
    2. Computational and Systems Biology

    Limits on information transduction through amplitude and frequency regulation of transcription factor activity

    Anders S Hansen, Erin K O'Shea
    The ability of cells to transmit information encoded in signaling dynamics is fundamentally limited by the gene decoding step.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

    Mona Seifert, Subhas C Bera ... David Dulin
    High-throughput and ultra-stable magnetic tweezers reveal that Remdesivir induces a long-lived backtrack pause upon incorporation by the coronavirus polymerase, and SARS-CoV-2 is able to evade interferon-induced antiviral ddhCTP.
    1. Neuroscience

    Rate-distortion theory of neural coding and its implications for working memory

    Anthony MV Jakob, Samuel J Gershman
    The abstract framework of rate-distortion theory can be realized by a neural population coding model to reproduce key and previously unexplained regularities of human visual working memory.

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