2,118 results found
    1. Neuroscience

    Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled

    Remi Ronzano, Sophie Skarlatou ... Marco Beato
    Multiple trans-synaptic tracing methods reveal that there is no spatial segregation between flexor and extensor premotor interneurons in the lumbar spinal cord.
    1. Neuroscience

    Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex

    Jeffrey Stedehouder, Demi Brizee ... Steven A Kushner
    The joint combination of interbranch distance and local caliber is sufficient to predict with high accuracy the distribution of myelin internodes along individual axons of neocortical GABAergic interneurons.
    1. Neuroscience

    Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network

    Sam A Booker, Harumi Harada ... Imre Vida
    Presynaptic GABAB receptors are highly expressed and strongly suppress synaptic transmission at the input and output of hippocampal somatostatin interneurons.
    1. Neuroscience

    Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy

    Brielle Ferguson, Cameron Glick, John R Huguenard
    Targeting reductions in prefrontal PV interneuron activity and gamma power during cue presentation can rescue attention impairments in a mouse model of absence epilepsy.
    1. Neuroscience

    Somatostatin interneurons activated by 5-HT2A receptor suppress slow oscillations in medial entorhinal cortex

    Roberto de Filippo, Benjamin R Rost ... Dietmar Schmitz
    Somatostatin interneurons are novel mediators of serotonergic modulation in entorhinal cortex via activation of 5-HT2A receptors, a receptor involved in the etiology of different psychiatric disorders.
    1. Cell Biology
    2. Neuroscience

    Miro1-dependent mitochondrial dynamics in parvalbumin interneurons

    Georgina Kontou, Pantelis Antonoudiou ... Josef T Kittler
    Cell imaging and electrophysiology in the mouse hippocampus reveal a crucial role for the spatiotemporal regulation of mitochondrial dynamics in PV+ interneurons on cell morphology, network activity, and behavior.
    1. Neuroscience

    Predominantly linear summation of metabotropic postsynaptic potentials follows coactivation of neurogliaform interneurons

    Attila Ozsvár, Gergely Komlósi ... Gábor Tamás
    Summation of metabotropic GABAergic responses remain linear even if most superficial layer interneurons specialized to recruit GABAB receptors are simultaneously active.
    1. Developmental Biology
    2. Neuroscience

    Maf and Mafb control mouse pallial interneuron fate and maturation through neuropsychiatric disease gene regulation

    Emily Ling-Lin Pai, Jin Chen ... John LR Rubenstein
    Maf and Mafb differentially regulate MGE-derived cortical and hippocampal interneuron subtype and regional fate in part through promoting the expression of Mef2c and Pnoc during mouse embryonic neurogenesis.
    1. Developmental Biology
    2. Neuroscience

    Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons

    Matthieu Genestine, Daisy Ambriz ... Edmund Au
    Species-specific timing of interneuron migration across mice and humans is regulated by two vascular-derived factors, SPARC and SerpinE1.
    1. Computational and Systems Biology
    2. Neuroscience

    Stochastic and deterministic dynamics of intrinsically irregular firing in cortical inhibitory interneurons

    Philipe RF Mendonça, Mariana Vargas-Caballero ... Hugh PC Robinson
    A-type potassium conductances influence the distinctive firing behaviour of irregular-spiking interneurons.

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