Simultaneous voltage and calcium two-photon imaging of Purkinje neuron dendrites in awake mice reveals multiple interplaying mechanisms underlying sensory-evoked dendritic coincidence detection of parallel fiber and climbing fiber input.

The first malacostracan genome sequence will establish the genetically tractable Parhyale hawaiensis as a model organism in this key animal group.

Lineage transformation in lung cancer is dictated by ERK activity and requires permissive chromatin alterations in the context of targeted therapy resistance.

A genome-wide catalog of the regulatory effects of variants that separate modern humans from archaic humans.

The genome of a tiny tomato pest reveals mechanisms that underlie metazoan genome reduction.

The generation of high-quality little skate reference genome enables molecular mechanism studies of gene regulation.

The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.

The model organism Tetrahymena thermopile carries two nuclei with distinct genomes: an unrearranged germline genome with five chromosomes, and a somatic genome reduced in size by a third and with 181 chromosomes.

Genetic predisposition to uterine leiomyomas arises from variation at loci for genetic stability and genitourinary development, and in part explains the frequent occurrence of the condition in women with African origin.

Mammalian fertilization is accomplished through integrating various molecular pathways that include evolutionarily conserved factors, DCST1 and DCST2.