Lateral gene transfer is unable to resist mutation accumulation in large genomes, leading to selective pressure for the origin of meiotic sex in the first eukaryotes.
Alex de Mendoza, Hiroshi Suga ... Iñaki Ruiz-Trillo
Functional genomics reveal complex genome regulation during the coenocytic development of the ichthyosporean Creolimax fragrantissima, a protist closely related to animals.
Alessandro W Rossoni, Dana C Price ... Andreas PM Weber
Horizontal gene transfer (HGT) analysis in polyextremophile red algae (Cyanidiales) provides explanations for the nonexistence of cumulative effects and eukaryotic pangenomes, and highlights differences between HGT and native genes.
A number of microbial eukaryotes have adapted to low oxygen conditions by acquiring a gene that allows their mitochondrial electron transport chain to continue to function when oxygen is scarce.
Carla Gonçalves, Jennifer H Wisecaver ... Paula Gonçalves
Comparative genomics coupled with genetic and biochemical studies show that central carbon metabolism in fungi can be remodeled by genes originating from bacteria.
An in silico reconstruction of a chloroplast that existed hundreds of millions of years ago casts new insights in the evolutionary processes, endosymbioses and chimerism events that shape the origin of plastids.
Hua-Qian Yang, Marta Pérez-Hernández ... William A Coetzee
The functional interaction of Na+ and KATP channels at the intercalated disk of cardiomyocytes depends on Ankyrin G and is clinically relevant since KATP channel mutations affect Na+ channel expression.