A novel immunoassay for ApoB-100, the main protein component of lipoproteins, enables the development of methods to enrich extracellular vesicles from human plasma while depleting both lipoproteins and free proteins.
Jerome Robert, Emily B Button ... Cheryl L Wellington
Modelling beta-amyloid deposition in bioengineered human vessels represents a notable advance to further investigate the role of the vasculature in Alzheimer's disease.
Christopher Icke, Freya J Hodges ... Ian R Henderson
AatD is a novel acyltransferase that mediates N-palmitoylation of glycine, a process not previously described, that results in the secretion of lipoproteins to the bacterial cell surface.
The expression of the lipoprotein lipase (LPL) transporter GPIHBP1 in glioma capillaries promotes the LPL-mediated processing of triglyceride-rich lipoproteins, thereby providing lipid nutrients for glioma cells.
Simon Mysling, Kristian Kølby Kristensen ... Michael Ploug
Intravascular triglyceride hydrolysis by lipoprotein lipase is crucial for delivering lipid nutrients to vital tissues, such as the heart, skeletal muscle, and adipose tissue.
High-density lipoprotein (HDL) subfraction traits appear to have heterogeneous effects on coronary artery disease, giving support to the HDL function hypothesis.
Marko Brankatschk, Sebastian Dunst ... Suzanne Eaton
Yeast specific lipids promote the transport of lipid transfer protein (LTP) across the blood brain barrier to the neurons that regulate systemic insulin signaling.
Aaron G Wexler, Whitman B Schofield ... Andrew L Goodman
The human gut bacterial lipoprotein BtuG binds vitamin B12 with femtomolar affinity, can remove vitamin B12 from human intrinsic factor, and is required for commensal fitness in the gut.