14,377 results found
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition

    Li Hou, Pengcheng Yang ... Le Kang
    Two neuropeptides, NPF1a and NPF2, act via the nitric oxide signaling pathway in the locust brain to regulate the trait transition between solitary and swarming behavior.
    1. Cell Biology

    Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

    Ding Ding, Jie Zhang ... Le Kang
    The long-distance flight of locusts is greatly facilitated by a muscle-abundantly expressed Hif-1α splice variant, which remains active in normoxia and scavenges flight-induced reactive oxygen species by upregulating the expression of DJ-1 (PARK 7).
    1. Evolutionary Biology

    A β-carotene-binding protein carrying a red pigment regulates body-color transition between green and black in locusts

    Meiling Yang, Yanli Wang ... Le Kang
    Body color change of locusts reveals a new 'palette effect' mechanism by which the red βCBP–β-carotene pigment complex acts as a switch to coordinate between black and green coloration.
    1. Biochemistry and Chemical Biology
    2. Ecology

    Aggregation pheromone 4-vinylanisole promotes the synchrony of sexual maturation in female locusts

    Dafeng Chen, Li Hou ... Xianhui Wang
    4-Vinylanisole acts as maturation-accelerating pheromone to synchronize oocyte maturation of female adults in locusts.
    1. Genetics and Genomics
    2. Neuroscience

    Neuropeptide ACP facilitates lipid oxidation and utilization during long-term flight in locusts

    Li Hou, Siyuan Guo ... Xianhui Wang
    CRISPR/Cas 9 technology and multiple-omics study reveal an essential regulatory role of neuropeptide ACP in lipid utilization related to prolonged flight of locusts.
    1. Plant Biology

    Epidermal LysM receptor ensures robust symbiotic signalling in Lotus japonicus

    Eiichi Murakami, Jeryl Cheng ... Simona Radutoiu
    Functional analyses provide evidence for a complex Nod factor signalling where NFRe is necessary for maintaining an optimal symbiotic signalling in the susceptible root zone, and initiation of nodule primordia on the expanding root system.
    1. Computational and Systems Biology
    2. Neuroscience

    Cellular composition and circuit organization of the locus coeruleus of adult mice

    Andrew McKinney, Ming Hu ... Xiaolong Jiang
    Interrogating mouse locus coeruleus via large-scale multipatch whole-cell recordings uncovers its cellular heterogeneity and cell-type-specific wiring logic.
    1. Neuroscience

    Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation

    Josué Haubrich, Matteo Bernabo, Karim Nader
    The overactivation of noradrenergic inputs to the amygdala during severe fear learning increases memory stability at the expense of lability, rendering the trace resistant to memory destabilization and reconsolidation.
    1. Computational and Systems Biology
    2. Ecology

    The LOTUS initiative for open knowledge management in natural products research

    Adriano Rutz, Maria Sorokina ... Pierre-Marie Allard
    The LOTUS initiative builds, through the Wikidata knowledge graph, a virtuous cycle of data sharing practices for natural products research.
    1. Genetics and Genomics
    2. Neuroscience

    The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

    Lukas M Weber, Heena R Divecha ... Stephanie C Hicks
    Spatially-resolved transcriptomics and single-nucleus RNA-sequencing are applied to the human locus coeruleus to characterize the gene expression profiles of norepinephrine (NE) neurons and other cell populations in this critical brain region, with all data made publicly available.

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