2,440 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Long-distance communication by specialized cellular projections during pigment pattern development and evolution

    Dae Seok Eom, Emily J Bain ... David M Parichy
    Cells of the xanthophore lineage form projections that allow them to communicate with other pigment cells during adult pigment pattern formation in zebrafish, but not in the closely-related pearl danio.
    1. Developmental Biology
    2. Cell Biology

    Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal

    Ariel M Pani, Bob Goldstein
    Free, extracellular dispersal of Wnt proteins generates a long-range gradient during animal development and is required for signaling.
    1. Plant Biology

    Phloem unloading in Arabidopsis roots is convective and regulated by the phloem-pole pericycle

    Timothy J Ross-Elliott, Kaare H Jensen ... Karl J Oparka
    A study of solute and macromolecule trafficking in plants reveals a previously undescribed route for carbon distribution in growing root tissues.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Cohesin-dependence of neuronal gene expression relates to chromatin loop length

    Lesly Calderon, Felix D Weiss ... Matthias Merkenschlager
    Cohesin is required for the expression of neuronal genes that engage in long chromatin loops, while short-range enhancer-promoter loops can form in the absence of cohesin.
    1. Neuroscience

    BDNF/TrkB signaling endosomes in axons coordinate CREB/mTOR activation and protein synthesis in the cell body to induce dendritic growth in cortical neurons

    Guillermo Moya-Alvarado, Reynaldo Tiburcio-Felix ... Francisca C Bronfman
    BDNF axonal signaling regulates protein synthesis in neuronal cell bodies leading to dendritic arborization through dynein-dependent transport of signaling endosomes.
    1. Cell Biology

    Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

    Ding Ding, Jie Zhang ... Le Kang
    The long-distance flight of locusts is greatly facilitated by a muscle-abundantly expressed Hif-1α splice variant, which remains active in normoxia and scavenges flight-induced reactive oxygen species by upregulating the expression of DJ-1 (PARK 7).
    1. Developmental Biology

    Cytoneme-mediated cell-cell contacts for Hedgehog reception

    Laura González-Méndez, Irene Seijo-Barandiarán, Isabel Guerrero
    Direct interaction between Hedgehog-sending and Hedgehog-receiving cytonemes is a fundamental mechanism for morphogen transfer and gradient establishment.
    1. Computational and Systems Biology
    2. Developmental Biology

    The pattern of nodal morphogen signaling is shaped by co-receptor expression

    Nathan D Lord, Adam N Carte ... Alexander F Schier
    Ligand capture by cell surface receptor complexes sets the shape of the Nodal signaling pattern in zebrafish.
    1. Cell Biology
    2. Developmental Biology

    Glypicans define unique roles for the Hedgehog co-receptors boi and ihog in cytoneme-mediated gradient formation

    Eléanor Simon, Carlos Jiménez-Jiménez ... Isabel Guerrero
    The glypicans Dally-like protein and Dally reveal functional non-redundancy of the Hedgehog co-receptors Boi and Ihog through independent interactions and specifically regulate cytoneme dynamics via the Ihog FNIII domain, thus setting long-range signaling.
    1. Plant Biology

    Testing the Münch hypothesis of long distance phloem transport in plants

    Michael Knoblauch, Jan Knoblauch ... N Michele Holbrook
    Measurements of physiological and geometrical parameters of the sieve tube system in Ipomoea nil provide strong support for pressure driven mass flow.

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