1,625 results found
    1. Neuroscience

    A longitudinal study of Caenorhabditis elegans larvae reveals a novel locomotion switch, regulated by Gαs signaling

    Stanislav Nagy, Charles Wright ... David Biron
    C. elegans exhibits two distinct behavioural macro-states, active and quiet wakefulness, and protein kinase A regulates switching between these two states.
    1. Epidemiology and Global Health
    2. Neuroscience

    Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study

    Laurenz Lammer, Frauke Beyer ... A Veronica Witte
    Analyses of longitudinal neuroimaging data highlight the importance of social contact for brain health.
    1. Immunology and Inflammation
    2. Medicine

    Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death

    Jack Gisby, Candice L Clarke ... James E Peters
    Severe COVID-19 is characterised by a plasma proteomic biomarker signature, indicating innate immune activation, leucocyte–endothelial interactions, and epithelial injury.
    1. Epidemiology and Global Health
    2. Medicine

    Ontogeny of circulating lipid metabolism in pregnancy and early childhood – a longitudinal population study

    Satvika Burugupalli, Adam Alexander T Smith ... Barwon Infant Study Investigator team
    Plasma lipidomic profiling in pregnancy, infancy and early childhood provides a framework to define the relationship between lipid metabolism and health outcomes in early childhood.
    1. Medicine

    Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing

    Corrado Sandini, Daniela Zöller ... Stephan Eliez
    A novel methodical approach aimed at improving translation of network analyses to psychopathology provides an intuitive representation of longitudinal clinical pathways between symptoms and can assist in predicting prognosis.
    1. Epidemiology and Global Health
    2. Medicine

    Antibody levels following vaccination against SARS-CoV-2: associations with post-vaccination infection and risk factors in two UK longitudinal studies

    Nathan J Cheetham, Milla Kibble ... Claire J Steves
    Third SARS-CoV-2 vaccination appears to eliminate disparities in anti-Spike antibodies between those who received Pfizer-BioNTech versus Oxford/AstraZeneca for first and second vaccination, but levels remain lower in certain groups such as those on the UK 'Shielded Patient List'.
    1. Epidemiology and Global Health

    Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up

    Xia Li, Alexander Ploner ... Sara Hägg
    Biological ages have the potential to provide aging-related information beyond chronological age and can be predictive of mortality independently of both chronological age and different types of biological ages.
    1. Genetics and Genomics

    Genetic insights into ossification of the posterior longitudinal ligament of the spine

    Yoshinao Koike, Masahiko Takahata ... Shiro Ikegawa
    A GWAS meta-analysis for OPLL identified fourteen significant genomic loci and a subsequent Mendelian randomization study provided genetic evidence for a causal effect of obesity on the pathogenesis of OPLL, especially one of its subtypes, thoracic OPLL.
    1. Neuroscience

    Unraveling the developmental dynamic of visual exploration of social interactions in autism

    Nada Kojovic, Sezen Cekic ... Marie Schaer
    Children with ASD showed a significant divergence in gaze patterns compared to typically developing children, intensifying over early childhood, with implications for developmental and adaptive functioning.
    1. Neuroscience

    Robust group- but limited individual-level (longitudinal) reliability and insights into cross-phases response prediction of conditioned fear

    Maren Klingelhöfer-Jens, Mana R Ehlers ... Tina B Lonsdorf
    Reliability and predictability analyses beyond standard measures provide empirically based guidance regarding the design of fear conditioning tasks to assess individual differences and group-level inferences cross-sectionally and longitudinally.

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