2,094 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure

    Romain F Laine, Gemma Goodfellow ... Clemens F Kaminski
    Machine learning in conjunction with super-resolution imaging allows for the first time to quantitatively analyse large and heterogenous virus samples structure at a high throughput and specificity.
    1. Genetics and Genomics
    2. Neuroscience

    Machine learning sequence prioritization for cell type-specific enhancer design

    Alyssa J Lawler, Easwaran Ramamurthy ... Andreas R Pfenning
    A new cross-species machine learning-based strategy is applied to find enhancers that specifically label parvalbumin neurons in the mouse and macaque.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy

    Sierra M Barone, Alberta GA Paul ... Jonathan M Irish
    Rare, virus-specific immune cells in human blood are automatically identified by machine learning algorithm T-REX and characterized for signature features needed for tracking and isolation.
    1. Neuroscience

    Machine learning-assisted fluoroscopy of bladder function in awake mice

    Helene De Bruyn, Nikky Corthout ... Thomas Voets
    A new combined approach using X-ray fluoroscopy and machine learning provides detailed new insights into bladder function in awake, unrestrained mice and unveils important limitations of current approaches to study bladder function.
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    1. Computational and Systems Biology

    Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells

    Nalin Leelatian, Justine Sinnaeve ... Jonathan M Irish
    A new automated and unsupervised algorithm, Risk Assessment Population IDentification, identifies risk-stratifying cells in single cell datasets with robust statistical and biological validation.
    1. Cell Biology
    2. Computational and Systems Biology

    Active machine learning-driven experimentation to determine compound effects on protein patterns

    Armaghan W Naik, Joshua D Kangas ... Robert F Murphy
    In an investigation into the effects of drugs on proteins, an active machine learning algorithm chose which sets of experiments to perform and was able to learn an accurate model of the effects after doing only a fraction of the experiments.
    1. Neuroscience

    Cellular cartography of the organ of Corti based on optical tissue clearing and machine learning

    Shinji Urata, Tadatsune Iida ... Shigeo Okabe
    A method of generating comprehensive maps of cochlear cells was created and enabled researchers to study characteristics of cellular damage in aged and noise-exposed inner ear.
    1. Computational and Systems Biology
    2. Neuroscience

    Action detection using a neural network elucidates the genetics of mouse grooming behavior

    Brian Q Geuther, Asaf Peer ... Vivek Kumar
    A machine learning method for action detection is developed and applied toward mouse grooming behavior.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Bayesian machine learning analysis of single-molecule fluorescence colocalization images

    Yerdos A Ordabayev, Larry J Friedman ... Douglas L Theobald
    A physics-based, statistically rigorous mathematical model enables automated, objective interpretation of images from single-molecule fluorescence colocalization microscopy experiments.
    1. Cell Biology
    2. Immunology and Inflammation

    Non-invasive classification of macrophage polarisation by 2P-FLIM and machine learning

    Nuno GB Neto, Sinead A O'Rourke ... Michael G Monaghan
    Human blood derived macrophage polarisation can be classified by proxy of their metabolism, using advanced microscopy techniques generating single-cell parameters that are clustered and validated using machine learning classification models.

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