Longstanding eco-evolutionary theories are tested using shotgun metagenomic data from the human gut microbiome, showing links between community diversity and the evolutionary trajectory of a focal species within the community.

A new perception of the organization of T-cell receptor repertoires in mice and humans, based on high-throughput sequencing and CDR3 sequence similarity, indicates hubs of cross-species public sequences forming evolutionary conserved 'foci of attention' of T cell immunity.

To effectively ward off some of the most damaging groups of filamentous pathogens, plants rely on an evolutionarily conserved syntaxin function to block the pathogen from entering the host cell and proliferate.

NODAL/Activin-induced SMAD2 binding directly drives remodeling of both open and closed chromatin and does not directly correlate with temporal patterns of gene expression upon prolonged signaling.

TRIP13 inactivates the spindle assembly checkpoint by converting MAD2 from its active ‘closed’ state to its inactive ‘open’ state.

A key transcription-factor for osteogenic differentiation, PLZF, acts as a transcriptional activator by binding to active developmental enhancers and facilitates mediator recruitment, but is not involved in enhancer looping.

Experimental manipulations of social groups of ostriches show that the benefits of cooperative parental care for females, and the costs of sexual competition for males, lead to sex differences in optimal group sizes.

Jumping of transposable elements provides DNA-binding sites for the MADS-box transcription factor PHERES1, allowing the regulation of imprinted genes and other key endosperm development genes.

Mitosis of reduplicated chromosomes is under careful regulation and can be perfectly executed.

Microbiomediversity favors further diversity in a positive feedback that is strongest in lower-diversity biomes but which plateaus as niches are increasingly filled in higher-diversity biomes.