225 results found
    1. Medicine
    2. Epidemiology and Global Health

    Mapping residual transmission for malaria elimination

    Robert C Reiner Jr, Arnaud Le Menach ... David L Smith
    A fine-grain map of residual transmission and importation in Swaziland shows where to target malaria elimination efforts.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Genetic surveillance in the Greater Mekong subregion and South Asia to support malaria control and elimination

    Christopher G Jacob, Nguyen Thuy-Nhien ... Olivo Miotto
    Large-scale genetic surveillance of malaria implemented by National Malaria Control Programmes informs public health decision makers about the spread of strains resistant to antimalarials.
    1. Epidemiology and Global Health

    Determinants of MDA impact and designing MDAs towards malaria elimination

    Bo Gao, Sompob Saralamba ... Ricardo Aguas
    The impact of mass intervention campaigns is determined by the interaction between implementation logistics, patterns of human mobility and how transmission risk is distributed over space.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Potential herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations

    Daniel M Parker, Sai Thein Than Tun ... François Nosten
    Given sufficient population adherence, mass drug administration for falciparum malaria can provide group level benefits, also known as ‘herd effects’.
    1. Epidemiology and Global Health

    Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa

    Sofonias Tessema, Amy Wesolowski ... Bryan Greenhouse
    Combining parasite genetic and human mobility data can provide detailed information on local and cross-border connectivity, allowing programs to strengthen local and regional coordination for successful elimination of malaria.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

    Ellie Sherrard-Smith, Katarzyna A Sala ... Andrew M Blagborough
    Combining pre-erythrocytic and transmission blocking antibodies enhances the overall control and potential elimination of malaria within both mosquito and vertebrate populations.
    1. Microbiology and Infectious Disease
    2. Medicine

    A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

    Isaie J Reuling, Lisanne A van de Schans ... Teun Bousema
    Controlled human malaria infection model allows the study of gametocyte biology and dynamics providing novel insights and tools in malaria transmission and elimination efforts.
    1. Epidemiology and Global Health

    Mapping imported malaria in Bangladesh using parasite genetic and human mobility data

    Hsiao-Han Chang, Amy Wesolowski ... Caroline Buckee
    Human mobility drives malaria importation within countries and threatens elimination interventions, but can be measured using new approaches that combine parasite genetics, mobile phone data, travel surveys and models.
    1. Epidemiology and Global Health

    Spatio-temporal associations between deforestation and malaria incidence in Lao PDR

    Francois Rerolle, Emily Dantzer ... Adam Bennett
    Deforestation near villages is associated with short-term increases but long-term decreases in malaria incidence in Lao PDR, highlighting the influence of forest-going populations on malaria transmission in the region.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis

    James A Watson, Robert J Commons ... Nicholas J White
    The currently recommended adult dose of tafenoquine is insufficient for radical cure in all adults.

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