3,805 results found
    1. Ecology

    Drivers of species knowledge across the tree of life

    Stefano Mammola, Martino Adamo ... Ricardo A Correia
    Different species-level characteristics and sociocultural factors influence scientific and societal interest in biodiversity, with important implications for species-level conservation and dissemination.
    1. Ecology

    Mammal communities are larger and more diverse in moderately developed areas

    Arielle Waldstein Parsons, Tavis Forrester ... Roland Kays
    Citizen science camera trapping showing suburban and wild areas maintain similar levels of mammalian diversity and relative abundance, challenging conventional thoughts about the impacts of urbanization on wildlife.
    1. Ecology

    Mammals adjust diel activity across gradients of urbanization

    Travis Gallo, Mason Fidino ... Seth B Magle
    Mammals use time along the 24-hr cycle to reduce risk, adapt, and therefore persist in urban ecosystems.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Viruses are a dominant driver of protein adaptation in mammals

    David Enard, Le Cai ... Dmitri A Petrov
    Viruses drive adaptation at the scale of the whole proteome and not only in antiviral proteins in mammalian hosts.
    1. Developmental Biology
    2. Immunology and Inflammation

    Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice

    Ying Wang, Thomas S Chaffee ... Kathryn L Schwertfeger
    A distinct resident macrophage subpopulation that localizes to the adipose stroma and fibrous capsule of the nulliparous mammary gland and to extracellular matrix-enriched stroma surrounding mammary tumors is identified.
    1. Developmental Biology
    2. Immunology and Inflammation

    Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism

    Chew Leng Lim, Yu Zuan Or ... Valerie Chun Ling Lin
    Estrogen aggravates mammary involution through lysosome-mediated cell death, neutrophil recruitment via CXCR2 signalling, neutrophil-mediated inflammation and adipocyte repopulation.
    1. Developmental Biology
    2. Cancer Biology

    RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells

    Maaike PA van Bragt, Xin Hu ... Zhe Li
    Loss of RUNX1, a key regulator of estrogen receptor-positive luminal breast cells, impairs mammary epithelial differentiation and contributes to luminal breast cancer via genetic interactions with a loss of p53 or RB1.
    1. Cell Biology

    Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals

    Fabian Schueren, Thomas Lingner ... Sven Thoms
    Whole-genome in silico screening for stop codon contexts that produce elevated translational readthrough and peroxisome targeting reveals that in mammals, the amount of lactate dehydrogenase in the peroxisome is controlled by translational readthrough.
    1. Evolutionary Biology
    2. Neuroscience

    A cerebellar substrate for cognition evolved multiple times independently in mammals

    Jeroen B Smaers, Alan H Turner ... Chet C Sherwood
    Multiple independent directional selection events on a neural substrate that underpins domain-general associative abilities partly explains independent occurrences of complex behavior in different lineages of mammals.
    1. Developmental Biology

    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland

    Qiang Lan, Ewelina Trela ... Marja L Mikkola
    Live imaging, transcriptional profiling and mouse models demonstrated that the mesenchyme controls the growth pace but not the mode of branching of the mammary epithelium and unveiled a unique function for Igf1/Igfr1 in embryonic development mammary gland.

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