3,861 results found
    1. Ecology

    Signaling cascades and the importance of moonlight in coral broadcast mass spawning

    Paulina Kaniewska, Shahar Alon ... Oren Levy
    Artificial light causes changes to gene expression and cellular signaling cascades that coordinate mass spawning events for a species of coral from the Great Barrier Reef.
    1. Developmental Biology
    2. Immunology and Inflammation

    Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis

    Amir Hossein Kayvanjoo, Iva Splichalova ... Elvira Mass
    Identification of distinct yolk sac-derived macrophage subpopulations in the fetal liver reveals their crucial role in shaping the hematopoietic niche, impacting erythropoiesis and granulopoiesis through direct interactions with long-term hematopoietic stem cells.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Discovery of methylfarnesoate as the annelid brain hormone reveals an ancient role of sesquiterpenoids in reproduction

    Sven Schenk, Christian Krauditsch ... Florian Raible
    A small brain-derived lipid prevents bristle worms from entering maturation and death, challenging current views of hormone evolution and pesticide specificity.
    1. Biochemistry and Chemical Biology
    2. Stem Cells and Regenerative Medicine

    SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells

    Samuel A Myers, Sailaja Peddada ... Barbara Panning
    A post-translational modification called O-GlcNAcylation modulates the activity of the SOX2 transcription factor in pluripotent stem cells.
    1. Chromosomes and Gene Expression

    An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning

    Irene Díaz-López, René Toribio ... Iván Ventoso
    The ES6S region of the small subunit ribosome makes a place for the threading and secondary structure unwinding of mRNA, which regulates genome-wide translation.
    1. Ecology

    Mass Spawning: Sex under the moon

    Didier Zoccola, Sylvie Tambutté
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  1. December 2015

    Episode 26: December 2015

    In this episode we hear about heat-seeking behaviour in mosquitos, mass spawning in coral reefs, social organization in ants, fear in rats and tissue regeneration in newts.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Improving oligo-conjugated antibody signal in multimodal single-cell analysis

    Terkild B Buus, Alberto Herrera ... Sergei B Koralov
    Oligo-conjugated antibodies are a powerful tool but require thorough optimization to reduce background signal, increase sensitivity, and reduce sequencing costs.
    1. Cell Biology
    2. Medicine

    Csf1 from marrow adipogenic precursors is required for osteoclast formation and hematopoiesis in bone

    Leilei Zhong, Jiawei Lu ... Ling Qin
    Bone marrow adipogenic precursors synthesize Csf1 to control bone remodeling and hematopoiesis.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Genetic mapping of etiologic brain cell types for obesity

    Pascal N Timshel, Jonatan J Thompson, Tune H Pers
    Unbiased computational integration of single-cell- and human genetics data shows that susceptibility to obesity is driven by a broad set of neuronal populations across the brain.

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