1,314 results found
    1. Developmental Biology
    2. Plant Biology

    Mechanical stress contributes to the expression of the STM homeobox gene in Arabidopsis shoot meristems

    Benoît Landrein, Annamaria Kiss ... Olivier Hamant
    Mechanical stress promotes the expression of the homeobox gene and meristem master regulator STM, synergistically and independently from auxin depletion.
    1. Cell Biology
    2. Plant Biology

    Subcellular and supracellular mechanical stress prescribes cytoskeleton behavior in Arabidopsis cotyledon pavement cells

    Arun Sampathkumar, Pawel Krupinski ... Elliot M Meyerowitz
    In the Arabidopsis epidermis, the internal mechanical stress of a cell competes with the external stress to control microtubule behavior, providing a framework to understand the mechanical feedbacks that underlie plant morphogenesis.
    1. Cell Biology

    Caveolae couple mechanical stress to integrin recycling and activation

    Fidel-Nicolás Lolo, Dácil María Pavón ... Miguel A del Pozo
    Caveolae regulate integrin mechanosensing by establishing a force threshold for activation and recycling.
    1. Physics of Living Systems

    Extracellular matrix in multicellular aggregates acts as a pressure sensor controlling cell proliferation and motility

    Monika E Dolega, Sylvain Monnier ... Giovanni Cappello
    Theoretical predictions and experiments on multicellular aggregates indicate that the extracellular matrix acts as a mechanical sensor, which regulates cell proliferation and migration in a three-dimensional environment.
    1. Computational and Systems Biology
    2. Developmental Biology

    Why plants make puzzle cells, and how their shape emerges

    Aleksandra Sapala, Adam Runions ... Richard S Smith
    Puzzle-shape cells in the epidermis of many plants form due to a development constraint based on mechanical forces.
    1. Plant Biology

    A tension-adhesion feedback loop in plant epidermis

    Stéphane Verger, Yuchen Long ... Olivier Hamant
    Tensile stress patterns in tissues are revealed by cell-cell adhesion defects; in turn, cell responses to supracellular tension require cell-cell adhesion.
    1. Physics of Living Systems

    Generating active T1 transitions through mechanochemical feedback

    Rastko Sknepnek, Ilyas Djafer-Cherif ... Silke Henkes
    Directed mechanical stresses can trigger active T1 events that lead to tissue elongation perpendicular to the main direction of tissue stress.
    1. Cancer Biology
    2. Cell Biology

    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

    Deborah Fanfone, Zhichong Wu ... Gabriel Ichim
    A biomechanical approach inducing confined cell migration reveals that mechanical stress has a profound effect on cancer cell survival.
    1. Developmental Biology

    Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling

    Kerim B Kaylan, Ian C Berg ... Gregory H Underhill
    Mechanical stress plays a cooperative role with Notch in biliary differentiation of liver progenitors, supporting a model of liver development in which biomechanical cues are key inducers of cell fate.
    1. Microbiology and Infectious Disease

    Biofilms deform soft surfaces and disrupt epithelia

    Alice Cont, Tamara Rossy ... Alexandre Persat
    The growth of multicellular bacterial structures called biofilms generates forces that deform soft material substrates and disrupt epithelial cell layers, potentially mechanically damaging host tissue.

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