Christoph A Bücherl, Iris K Jarsch ... Cyril Zipfel
Although genetically and biochemically linked, the plant immune and growth receptors FLS2 and BRI1 form dispersed receptor clusters within the plasma membrane that are spatiotemporally separated.
Julien Gronnier, Christina M Franck ... Cyril Zipfel
The perception of endogenous RALF signaling peptides modulates the plasma membrane nanoscale organization of receptor kinases to regulate plant immune signaling.
A canonical class III adenylate cyclase with a membrane anchor of six transmembrane spans is regulated by a receptor of similar design, the quorum-sensing receptor from Vibrio harveyi.
The mechanism of signaling receptor delivery to primary cilia involves a specific cellular role of a Rab protein that is critical for vertebrate development.
A new pathway is described involving the estrogen receptor alpha in the acute response of small arteries to flow independent of the ligand (estrogen) and of the nuclear signaling.
Ana Sofia Pinheiro, Vasilios Tsarouhas ... Christos Samakovlis
During tracheal morphogenesis, the scavenger receptor Emp senses and responds to luminal cargo levels by initiating apical membrane endocytosis along the longitudinal tube axis to restrict airway elongation.