82 results found
    1. Neuroscience

    Mapping cortical mesoscopic networks of single spiking cortical or sub-cortical neurons

    Dongsheng Xiao, Matthieu P Vanni ... Timothy H Murphy
    Mesoscale cortical calcium activity correlating with single cortical and thalamic cell spiking reveal rich dynamics and support a novel approach for investigating in vivo functional networks in the mammalian brain.
    1. Neuroscience

    Mesoscopic-scale functional networks in the primate amygdala

    Jeremiah K Morrow, Michael X Cohen, Katalin M Gothard
    Multivariate data decomposition applied to local field potentials recorded from the primate amygdala revealed simultaneously active and functionally distinct networks, defined by anatomical boundaries between the nuclei.
    1. Neuroscience

    Cortical network architecture for context processing in primate brain

    Zenas C Chao, Yasuo Nagasaka, Naotaka Fujii
    Large-scale electrocorticography and big data analysis of brain-wide neuronal interactions reveal the architecture of network information flow for context processing in primate brain.
    1. Neuroscience

    Neural mechanisms underlying the temporal organization of naturalistic animal behavior

    Luca Mazzucato
    Naturalistic animal behavior exhibits a complex organization in the temporal domain, whose variability stems from hierarchical, contextual, and stochastic sources and can be naturally explained in terms of metastable attractor models.
    1. Neuroscience

    Global organization of neuronal activity only requires unstructured local connectivity

    David Dahmen, Moritz Layer ... Moritz Helias
    Short-ranged and random connectivity are sufficient to explain complex, long-range activity patterns observed in macaque motor cortex that are, moreover, flexibly adaptable to behavior.
    1. Physics of Living Systems

    Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies

    Rachel A Banks, Vahe Galstyan ... Rob Phillips
    Mesoscopic properties of motor-microtubule assemblies, such as contractile rates and length scales, can be quantitatively connected to single-motor properties of kinesin motors.
    1. Computational and Systems Biology
    2. Neuroscience

    A simple generative model of the mouse mesoscale connectome

    Sid Henriksen, Rich Pang, Mark Wronkiewicz
    A realistic model of the connections between local populations of neurons in the adult mouse brain can be constructed based on just two biologically plausible rules.
    1. Cell Biology
    2. Physics of Living Systems

    Quantitative theory for the diffusive dynamics of liquid condensates

    Lars Hubatsch, Louise M Jawerth ... Christoph A Weber
    Dynamical properties of liquid condensates can be quantitatively assessed by combining phase separation theory and photobleaching, which opens new avenues to understand their physicochemical properties and functioning.
    1. Neuroscience

    Capturing the temporal evolution of choice across prefrontal cortex

    Laurence T Hunt, Timothy EJ Behrens ... Steven W Kennerley
    Experiments in macaques and humans reveal time-varying changes in prefrontal cortex activity that occur during decisions based on costs and benefits.
    1. Cell Biology
    2. Computational and Systems Biology

    Deciphering anomalous heterogeneous intracellular transport with neural networks

    Daniel Han, Nickolay Korabel ... Thomas A Waigh
    Direct estimation of the Hurst exponent shows that endosomes and lysosomes reside in regimes of persistent and anti-persistent motion with heavy-tailed residence time distributions and motion correlated with endocytic function.

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