A combination of chloroplast transformation with nuclear transformation and large-scale metabolic screening of supertransformed plant lines has enabled an entire biochemical pathway to be transferred from a medicinal plant to a high-biomass crop.
A new method for developing biosensors from ligand binding domains that have concentration-dependent and selective responses to small molecules in yeast, mammalian cells and plants.
Nathan Tague, Cristian Coriano-Ortiz ... Mary J Dunlop
The LOVdeg tag is a versatile tool for bacterial optogenetics, offering modular, blue light-inducible protein degradation for a range of synthetic biology and metabolic engineering applications.
Vishhvaan Gopalakrishnan, Dena Crozier ... Jacob G Scott
The EVolutionary biorEactor (EVE) can be built for less than $200, and can be used to evaluate microbial population dynamics in the lab and to teach evolution in high schools.
Constraint-based modelling predicts C4 photosynthesis evolves under resource limitation from an ancestral ground state of C3 photosynthesis and attributes divergent metabolic routes in extant C4 subtypes to light.
Frederic A Roemschied, Monika JB Eberhard ... Susanne Schreiber
The firing rates of neurons in the grasshopper auditory system are surprisingly robust to changes in temperature, and cell-intrinsic mechanisms are sufficient to explain this temperature insensitivity.
Valentina Baldazzi, Delphine Ropers ... Hidde de Jong
A coarse-grained model of microbial growth coupling fluxes of carbon and energy shows that resource allocation is a major explanatory factor of the observed variability of growth rates and growth yields across different bacterial strains.