11,766 results found
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Heterogeneous absorption of antimicrobial peptide LL37 in Escherichia coli cells enhances population survivability

    Mehdi Snoussi, John Paul Talledo ... Sattar Taheri-Araghi
    A rapid absorption and retention of antimicrobial peptides by dead Escherichia coli cells can increase the survivability of the cell population in a "cooperative" fashion.
    1. Neuroscience

    Evidence for dopaminergic involvement in endogenous modulation of pain relief

    Simon Desch, Petra Schweinhardt ... Susanne Becker
    Endogenous modulation of pain relief perception is based on its motivational content and enhanced by increased dopamine availability with no significant effects of a pharmacological opioidergic manipulation in healthy volunteers.
    1. Evolutionary Biology
    2. Genetics and Genomics

    On the limits of fitting complex models of population history to f-statistics

    Robert Maier, Pavel Flegontov ... David Reich
    Many published findings about population history that rely on inference of admixture graph models fitted to f-statistics are not robust since the method is generally inappropriate for extracting new information about population history.
    1. Neuroscience

    Spatial modulation of visual responses arises in cortex with active navigation

    E Mika Diamanti, Charu Bai Reddy ... Matteo Carandini
    Spatial modulation along the visual pathway arises in the cortex and strengthens with active navigation and experience.
    1. Neuroscience

    Population receptive fields in nonhuman primates from whole-brain fMRI and large-scale neurophysiology in visual cortex

    P Christiaan Klink, Xing Chen ... Pieter R Roelfsema
    Within-species comparison of population receptive fields determined with fMRI and electrophysiology in nonhuman primates reveals the neuronal basis of blood-oxygen-level-dependent-based retinotopy.
    1. Neuroscience

    Modulation of tonotopic ventral medial geniculate body is behaviorally relevant for speech recognition

    Paul Glad Mihai, Michelle Moerel ... Katharina von Kriegstein
    Ultra-high field neuroimaging dissects the ventral medial geniculate body (vMGB) of the primary auditory pathway from other MGB subregions and reveals that vMGB top-down modulation is relevant for speech recognition.
    1. Developmental Biology

    The zinc-finger transcription factor Hindsight regulates ovulation competency of Drosophila follicles

    Lylah D Deady, Wei Li, Jianjun Sun
    Hindsight/RREB-1 plays a conserved role in follicle maturation and ovulation by sequential upregulation of matrix metalloproteinase and adrenergic receptor in follicle cells.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde

    Iman Hamid, Katharine L Korunes ... Amy Goldberg
    Admixture-mediated adaptation to malaria in a human population demonstrates that detectible signatures in genomic patterns of ancestry can be leveraged to better characterize recent selection in populations with mixed ancestry.
    1. Evolutionary Biology

    Native American genetic ancestry and pigmentation allele contributions to skin color in a Caribbean population

    Khai C Ang, Victor A Canfield ... Keith C Cheng
    Analysis of 458 Kalinago provides new insights into the population's genetic structure, the contribution of Native American ancestry to skin pigmentation, and the identification of a coding variant in OCA2 with an estimated –8 melanin units effect size.
    1. Neuroscience

    Neural population dynamics of computing with synaptic modulations

    Kyle Aitken, Stefan Mihalas
    Synaptic modulations alone imbue networks with computational capabilities comparable to recurrent connections on several neuroscience-relevant tasks, which manifest in fundamentally different neuronal dynamics.

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