231 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes

    Miriam I Rosenberg, Ava E Brent ... Claude Desplan
    Pair-rule genes in the wasp Nasonia function as in Drosophila in patterning anterior segments, and similar to ancestral insects in patterning posterior segments, illustrating a mixed-mode transition state between short and long germ embryogenesis.
    1. Neuroscience

    The impact of task context on predicting finger movements in a brain-machine interface

    Matthew J Mender, Samuel R Nason-Tomaszewski ... Cynthia A Chestek
    Task changes, like increased force production or altered posture, decrease the accuracy of brain-machine interfaces predicting intended finger movements, however, understanding how neural activity changes with the altered biomechanics of the task may provide insights for generalizable decoder development.
    1. Developmental Biology
    2. Neuroscience

    Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci

    Sonia Q Sen, Sachin Chanchani ... Chris Q Doe
    Spatial factors generate neuroblast-specific open chromatin, thereby biasing the subsequent binding of transcription factors to produce neuroblast-specific neurons.
    1. Genetics and Genomics

    The genetic risk of gestational diabetes in South Asian women

    Amel Lamri, Jayneel Limbachia ... Sonia S Anand
    A type 2 diabetes polygenic risk score and family history of diabetes are strongly and independently associated with multiple gestational diabetes-related traits in women of South Asian descent.
    1. Computational and Systems Biology
    2. Neuroscience

    Adult-born granule cells improve stimulus encoding and discrimination in the dentate gyrus

    Diego M Arribas, Antonia Marin-Burgin, Luis G Morelli
    Heterogeneity in the population of granule cells in the dentate gyrus, which includes immature and mature neurons with distinct intrinsic properties, contributes to the population's enhanced encoding capabilities and ability to discriminate correlated stimuli.
    1. Neuroscience

    Differential inhibition onto developing and mature granule cells generates high-frequency filters with variable gain

    María Belén Pardi, Mora Belén Ogando ... Antonia Marin-Burgin
    Immature and mature granule cells in the hippocampal dentate gyrus show differing responses to physiologically relevant stimuli, with immature cells better at encoding stimulus frequency and mature cells better at encoding stimulus onset.
    1. Developmental Biology
    2. Neuroscience

    Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve

    Sonia Taïb, Noël Lamandé ... Isabelle Brunet
    Angiogenesis and vascular development within peripheral nerve is regulated by Netrin-1, Schwann cells, and myelination.
    1. Neuroscience

    Impaired adaptation of learning to contingency volatility in internalizing psychopathology

    Christopher Gagne, Ondrej Zika ... Sonia J Bishop
    Hierarchical modeling of internalizing symptoms and task performance reveals that difficulty adapting probabilistic learning to second-order uncertainty is common to anxiety and depression and holds across rewarding and punishing outcomes.
    1. Neuroscience

    Cholinergic modulation shifts the response of CA1 pyramidal cells to depolarizing ramps via TRPM4 channels with potential implications for place field firing

    Crescent L Combe, Carol M Upchurch ... Sonia Gasparini
    A nonspecific cation current mediated by TRPM4 channels is a major contributor to the increase in excitability induced by cholinergic modulation in hippocampal CA1 pyramidal neurons, which are thought to play an important role in episodic memory.
    1. Developmental Biology
    2. Evolutionary Biology

    Origin of the mechanism of phenotypic plasticity in satyrid butterfly eyespots

    Shivam Bhardwaj, Lim Si-Hui Jolander ... Antonia Monteiro
    A gradual, step-wise, physiological/molecular response of eyespot size to temperature is a likely adaptation to seasonal variation experienced in the habitat of Bicyclusanynana butterflies.

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