Neuregulins control the integration of specific excitatory and inhibitory synapses through subcellular sorting.

Genetic rescue experiments reveal that γ-secretase enzymes containing Aph1b subunits control signalling by type III neuregulin 1, with implications for schizophrenia.

Neuregulin1 is induced upon cardiac injury in adult zebrafish, and is sufficient to drive massive proliferative growth of the heart.

Motor exit point (MEP) glia utilize mechanisms most commonly attributed to neural crest cells for their development from spinal cord precursors.

The clinically approved HER2 inhibitor lapatinib causes HER2 and HER3 kinase domains to dimerise in a non-canonical, symmetric orientation, providing a platform for oligomerisation and predisposing to receptor-driven cell proliferation.

3D single cell imaging and genetic analyses reveal a new role of cardiac metabolism in cardiac wall morphogenesis.

Schwann cell induced quiescence of mechanosensory progenitor cells is mediated by inhibition of Wnt/β-catenin signaling.

Apelin signaling-dependent endocardial protrusions promote cardiac trabeculation through Nrg/ErbB/Erk signaling in zebrafish.

Single-cell RNA sequencing reveals Nrg1/ErbB2-induced metabolic reprogramming as a pivotal event for cardiomyocyte proliferation during heart regeneration.

Human skeletal muscle progenitors and motor neurons self-organize in three-dimensional co-culture to form functional neuromuscular junctions that developmentally mature from the embryonic to the adult state.