589 results found
    1. Genetics and Genomics
    2. Neuroscience

    Neuropeptide ACP facilitates lipid oxidation and utilization during long-term flight in locusts

    Li Hou, Siyuan Guo ... Xianhui Wang
    CRISPR/Cas 9 technology and multiple-omics study reveal an essential regulatory role of neuropeptide ACP in lipid utilization related to prolonged flight of locusts.
    1. Genetics and Genomics
    2. Neuroscience

    Neural clocks and Neuropeptide F/Y regulate circadian gene expression in a peripheral metabolic tissue

    Renske Erion, Anna N King ... Amita Sehgal
    Neuropeptide F/Y from neurons drives rhythmic expression of detoxification-related genes in a peripheral metabolic tissue in flies and mice.
    1. Neuroscience

    Imaging neuropeptide release at synapses with a genetically engineered reporter

    Keke Ding, Yifu Han ... David J Anderson
    A series of genetically-encoded fluorescent reporters that allow imaging of neuropeptide release in vivo, with sub-second temporal and nerve terminal-level spatial resolution are developed.
    1. Evolutionary Biology
    2. Neuroscience

    Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling

    Luis Alfonso Yañez-Guerra, Xingxing Zhong ... Maurice R Elphick
    Discovery of a novel neuropeptide signalling system in a deuterostome invertebrate reveals the evolutionary origin of prolactin-releasing peptide and its relationship with neuropeptides in protostome invertebrates.
    1. Developmental Biology
    2. Neuroscience

    Homeodomain protein Otp affects developmental neuropeptide switching in oxytocin neurons associated with a long-term effect on social behavior

    Einav Wircer, Janna Blechman ... Gil Levkowitz
    Experiments in zebrafish reveal a new role for a critical hypothalamic transcription factor, orthopedia, in controlling developmental neuropeptide balance in a discrete oxytocin-producing neuronal circuit whose disrupted development affects social behavior.
    1. Neuroscience

    Neuropeptide B mediates female sexual receptivity in medaka fish, acting in a female-specific but reversible manner

    Towako Hiraki-Kajiyama, Junpei Yamashita ... Kataaki Okubo
    In the brain of medaka fish, neuropeptide B acts directly downstream of estrogen in a female-specific but reversible manner to mediate female receptivity to male courtship.
    1. Neuroscience

    Genetic and neuronal regulation of sleep by neuropeptide VF

    Daniel A Lee, Andrey Andreev ... David A Prober
    Genetic experiments in zebrafish identify neuropeptide VF (NPVF) signaling and NPVF-expressing neurons as a novel vertebrate hypothalamic sleep-promoting system that is functionally conserved with invertebrates.
    1. Evolutionary Biology
    2. Neuroscience

    Tachykinin signaling inhibits task-specific behavioral responsiveness in honeybee workers

    Bin Han, Qiaohong Wei ... Jianke Li
    Neuropeptide tachykinin signaling acts as master regulator of behavioral specialization in honeybees by differentially modulating worker responsiveness to task-specific stimuli.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition

    Li Hou, Pengcheng Yang ... Le Kang
    Two neuropeptides, NPF1a and NPF2, act via the nitric oxide signaling pathway in the locust brain to regulate the trait transition between solitary and swarming behavior.
    1. Neuroscience

    Sleep-active neuron specification and sleep induction require FLP-11 neuropeptides to systemically induce sleep

    Michal Turek, Judith Besseling ... Henrik Bringmann
    The mechanisms of specification and sleep induction by the single sleep-active neuron are revealed in C. elegans.

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