An implantable device based on organic electrochemical transistors is developed for quantitative mapping of neurotransmitter release across multiple brain regions, revealing a cross-talk between the mesolimbic and nigrostriatal dopaminergic pathways.

Local brain functional activity reductions in bvFTD follow the distribution of serotonergic, GABAergic, and norepinephrinergic neurotransmitter systems, indicating a selective vulnerability and providing novel insights into the underlying disease mechanisms.

Dimensionality reduction techniques reveal how the organization of neurotransmitter receptor and transporter co-expression in the human brain may bridge the gap between brain structure and function.

Experience alters neurotransmitter release from different axonal compartments in different ways, allowing a set of neurons to coherently modulate behavior through diverse actions on multiple downstream circuits.

While neurotransmitters were discovered decades ago, evidence suggests that more transmitters are to be discovered using the presented approaches.

Lineally related neurons in the adult Drosophila ventral nerve cord use the same neurotransmitter to communicate with other neurons.

The crystal structure of a large C-terminal fragment of Munc13-1 provides a key framework to understand how Munc13-1 mediates neurotransmitter release and presynaptic plasticity.

Fluorescent glutamate indicators distort the time course of neurotransmitter diffusion and uptake by competing with transporters, an important caveat to consider when using iGluSnFR and its analogs.

Challenging a widespread model, biophysical and electrophysiological experiments suggest a new mechanism whereby complexins inhibit neurotransmitter release through electrostatic repulsion between their accessory helix and the membranes.

Neurotransmitter balance in a region in frontal cortex controls how much people use information they have learnt to guide their behaviour.