The organisation of the Drosophila embryo into segmental units is orchestrated by combinatorial regulatory interactions between spatially patterned and temporally patterned transcription factors.

Mechanisms for shaping the chromatin accessibility landscape operate during development to regulate how embryonic patterning information is interpreted at the level of gene regulatory networks.

The gene Odd-paired is a late-acting regulator of zygotic gene expression, functioning coordinately with Zelda to influence chromatin accessibility and affecting genes expressed along both axes of Drosophila embryos.

Odd-paired (opa) is required for the progression of temporal patterning in Drosophila neural progenitors to regulate temporal identities via an incoherent feed-forward loop.

Isoform-specific transcript localization underlies the evolutionary diversity of anterior axis determinants in embryos of dipteran insects.

Pair-rule genes in the wasp Nasonia function as in Drosophila in patterning anterior segments, and similar to ancestral insects in patterning posterior segments, illustrating a mixed-mode transition state between short and long germ embryogenesis.

A retracting gradient of the transcription factor Tailless spatiotemporally patterns the Drosophila tail region by modulating the intrinsic dynamics of a regulatory network involving the timer genes caudal, Dichaete, and odd-paired.

Four types of declarative memory rely on different weightings of similar component processes, according to fMRI and subjective ratings.

Scenario-invariant representation of physical stability is found in the frontoparietal regions but not the ventral visual pathway (and ImageNet-trained convolutional neural networks), consistent with the hypothesis that computations underlying physical stability may entail forward simulations of what will happen next.

A cryo-electron microscopy model of the active human apoptosome illuminates how this "wheel of death" binds the protease procaspase-9 to initiate programmed cell death.