2 results found
    1. Neuroscience

    Optocontrol of glutamate receptor activity by single side-chain photoisomerization

    Viktoria Klippenstein, Christian Hoppmann ... Pierre Paoletti
    Introduction of single photoswitchable unnatural amino acid into a neuronal receptor provides reversible, rapid and robust control of its activity by light, representing an important contribution to the fast expanding field of optopharmacology.
    1. Neuroscience

    Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

    Joan Font, Marc López-Cano ... Francisco Ciruela
    Localized drug photoactivation provides light-mediated analgesia in behaving mice.

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