Pierre Millard, Brice Enjalbert ... Fabien Létisse
Elucidating the control and regulation of acetate overflow in E. coli reveals that acetate is not only an end-product but also a co-substrate and a global regulator of glucose metabolism.
Sabina Siebert, Laura M. Machesky, Robert H. Insall
Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.
The proper development of the vocal cords requires embryos to contain a certain number of progenitor cells, and mutations that lead to an overflow of cells can cause malformations of the voice box.
Francisco Díaz-Pascual, Martin Lempp ... Knut Drescher
An investigation of spatiotemporal metabolic differentiation during colony biofilm growth of E. coli revealed that alanine is cross-fed between spatially segregated subpopulations within the colony, to support cellular growth in an otherwise nutrient-deprived region of the colony.
Cynthia B Silveira, Antoni Luque ... Forest Rohwer
Coral reef heterotrophic bacteria and fleshy macroalgae cause oxygen loss from reef systems through microbial biomass accumulation and ebullition from algae surfaces.
Valentina Baldazzi, Delphine Ropers ... Hidde de Jong
A coarse-grained model of microbial growth coupling fluxes of carbon and energy shows that resource allocation is a major explanatory factor of the observed variability of growth rates and growth yields across different bacterial strains.
Charles Ducrot, Gregory de Carvalho ... Louis-Eric Trudeau
A combination of electrophysiological, electrochemical, and anatomical experiments sheds new light on how the complex neurotransmitter repertoire of dopaminergic neurons in the brain is regulated by proteins of the neurexin family.
Sebastian Korb, Sebastian J Götzendorfer ... Giorgia Silani
Administration of dopamine and opioid receptor antagonists resulted in reduced reward anticipation (effort and increased negative facial reactions), but only administration of opioid antagonists resulted in reduced liking (facial reactions).