X-ray imaging reveals well-preserved internal characters in mineralized arthropods from the Paleogene, urging the reexamination of previously neglected fossil collections.

PARP-7 is a mono(ADP-ribosyl) transferase that directs an extensive ADP-ribosylated proteome to control microtubule stability, and regulate ovarian cancer cell growth and motility.

Nanodomain clustering of cAMP effectors represents a novel mechanism of cAMP compartmentation within an oscillatory signaling circuit.

The dynamic current generated Na⁺/K⁺ pump interacts with the h-current to control the bursting activity of oscillator heart interneurons.

Closely related type II-C Cas9 orthologs recognize diverse PAMs, which facilitates us to expand the targeting scope.

COV-ID is a highly scalable technology that utilizes a two-step barcoding strategy to detect viral RNAs in saliva samples combining RT-LAMP, PCR, and next generation sequencing.

Live cell imaging shows that the cAMP-sensor Epac2, a target of major antidiabetic drugs, is central to fusion pore control during insulin granule exocytosis.

Nuclei of the true slime mold Physarum polycephalum are continuously shuttled within the cytoplasmic flow across the gigantic syncytium, yet Physarum can establish and maintain gene expression heterogeneity between different structures of the organism.

Investigation of defined extracellular matrix proteins in differentiation of human pluripotent stem cells to cardiomyocytes reveals fibronectin, in addition to soluble factors, is required for cardiogenesis.

A combined chemical genetics, proximity labeling, and ADP-ribose site mapping approach shows that PARP-7 mono-ADP-ribosylates immune-relevant proteins on cysteine amino acids.