2,704 results found
    1. Developmental Biology
    2. Plant Biology

    Control of Arabidopsis shoot stem cell homeostasis by two antagonistic CLE peptide signalling pathways

    Jenia Schlegel, Gregoire Denay ... Rüdiger GW Simon
    Plant meristem size and shape is controlled by two intertwined regional feedback signals that are mediated by secreted peptides.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Stimulation strength controls the rate of initiation but not the molecular organisation of TCR-induced signalling

    Claire Y Ma, John C Marioni ... Arianne C Richard
    The strength of TCR signalling determines the rate at which cells initiate a tightly coordinated signalling programme, without altering its organization.
    1. Structural Biology and Molecular Biophysics
    2. Plant Biology

    Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission

    Julia Santiago, Benjamin Brandt ... Michael Hothorn
    A plant peptide hormone controls organ shedding by acting as molecular glue that promotes the interaction between two membrane receptor kinases.
    1. Developmental Biology

    Npr3 regulates neural crest and cranial placode progenitors formation through its dual function as clearance and signaling receptor

    Arun Devotta, Hugo Juraver-Geslin ... Jean-Pierre Saint-Jeannet
    A combination of morpholino-based knockdowns, pharmacological inhibitors, and rescue assays reveal a novel role for natriuretic peptide signaling in the regulation of cell fates in the embryonic ectoderm.
    1. Cell Biology
    2. Plant Biology

    Regulation of immune receptor kinase plasma membrane nanoscale organization by a plant peptide hormone and its receptors

    Julien Gronnier, Christina M Franck ... Cyril Zipfel
    The perception of endogenous RALF signaling peptides modulates the plasma membrane nanoscale organization of receptor kinases to regulate plant immune signaling.
    1. Neuroscience

    BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk

    Qing-Tao Meng, Xian-Yu Liu ... Zhou-Feng Chen
    B-type natriuretic peptide (BNP) modulates itch via BNP-NPRC pathway by enhancing NMB-NMBR signaling, which is independently of gastrin-releasing peptide (GRP)-GRPR signaling in the spinal cord.
    1. Evolutionary Biology
    2. Neuroscience

    Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling

    Luis Alfonso Yañez-Guerra, Xingxing Zhong ... Maurice R Elphick
    Discovery of a novel neuropeptide signalling system in a deuterostome invertebrate reveals the evolutionary origin of prolactin-releasing peptide and its relationship with neuropeptides in protostome invertebrates.
    1. Plant Biology
    2. Developmental Biology

    Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling

    Xingyun Qi, Soon-Ki Han ... Keiko U Torii
    The stomatal precursor cell uses autocrine peptide-receptor kinase signaling to self-inhibit its differentiation potential in order to ensure proper stomatal development on the plant epidermis.
    1. Developmental Biology
    2. Genetics and Genomics

    An alternatively spliced, non-signaling insulin receptor modulates insulin sensitivity via insulin peptide sequestration in C. elegans

    Bryan A Martinez, Pedro Reis Rodrigues ... Matthew S Gill
    A truncated, non-signaling insulin receptor regulates insulin sensitivity in the nematode C. elegans by sequestering insulin peptides and preventing their interaction with full length receptors.
    1. Plant Biology

    Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3

    Jack Rhodes, Andra-Octavia Roman ... Cyril Zipfel
    Identification of a new family of stress-induced plant signalling peptides and their cognate receptor.
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