In filamentous fungi the AP-2 complex, which in mammals is an adaptor of clathrin-mediated endocytosis, is recruited to specific clathrin-independent apical endocytosis necessary for proper lipid maintenance and polar growth.

The specification of cell polarity is essential for self-renewal and the segregation of stem-cell and daughter-cell fates in an epithelial stem cell lineage.

Planar cell polarity (PCP) components and myosin show a parallel temporal polarization in the Ciona notochord and the mutual interaction between these proteins is required for proper tissue-wide polarity.

Oon and Prehoda discover cortical actomyosin dynamics that polarize asymmetrically dividing neural stem cells.

Leaf position, shape and orientation are pre-patterned by cell type boundaries in the shoot meristem.

Contractility wins over the polarity pathway in a tug-of-war to position a cytokinesis-like actomyosin ring at the equator of notochord cells.

When challenged by energetic stresses triggered by hypoxia and ATP inhibition, plasma membrane PI4P and PIP2 in cells undergo dramatic turnovers that have profound impact on many cellular processes including electrostatic PM targeting of numerous polybasic proteins.

Activation of NOTCH signalling in different cell lineages of the embryonic murine pituitary uncovers an unexpected differential sensitivity, and this consequently reveals new aspects of endocrine lineages development and plasticity.

A minus-end-binding stabilizes minus-end-out microtubules in dendrites, which are required for dendrite-specific pruning during neuronal remodelling.

Infectosomes enabling polar progression of infection threads in legume roots require the symbioisis-related RPG protein that functions as an organizer of these structures.