The protozoan parasite Trypanosoma brucei gambiense has undergone recent clonal evolution that reveals the theoretically predicted Meselson effect at a genome-wide level.
Environmental heterogeneity can dramatically reduce the efficacy of selection and alter the neutral evolutionary dynamics in microbial range expansions.
Gillian Morven Belbin, Jacqueline Odgis ... Eimear E Kenny
A health-system embedding method for genomic discovery and clinical characterization of disease highlights the importance of documenting a wider spectrum of genetic disorders in diverse populations.
David Willemsen, Rongfeng Cui ... Dario Riccardo Valenzano
Population genetics in turquoise killifish wild populations reveals how small population size and genetic drift determine the accumulation of deleterious gene variants leading to short lifespan.
The coalescent history of a population can be learned just from the present genomic diversity, without having detailed prior knowledge of the pattern of recombination or the forces driving coalescence.
Whole genome deep sequencing of many longitudinally sampled HIV-1 populations reveals that reversions towards ancestral HIV-1 genome sequences occur throughout the course of infection.
The activation of transposable elements and relaxed purifying selection underpin an incipient expansion of the genome in populations of a major wheat pathogen.
Beatriz Navarro-Dominguez, Ching-Ho Chang ... Amanda M Larracuente
African haplotypes of a meiotic drive supergene in Drosophila melanogaster called Segregation Distorter show signs of a recent selective sweep, reduced recombination, and increased genetic load.
The same host–virus interactions can evolve multiple times in nature, due to the high effective mutation rate of viruses, and provide interesting systems of study.