13,875 results found
    1. Computational and Systems Biology
    2. Neuroscience

    A generalizable brain extraction net (BEN) for multimodal MRI data from rodents, nonhuman primates, and humans

    Ziqi Yu, Xiaoyang Han ... Jianfeng Feng
    The Brain Extraction Network (BEN) provides a robust, accurate, and generalizable solution not only for extracting brain tissue from multimodal MRI data in rodents, non-human primates, and humans, but also for improving the accuracy of downstream neuroimaging processing tasks.
    1. Evolutionary Biology
    2. Neuroscience

    The evolution and biological correlates of hand preferences in anthropoid primates

    Kai R Caspar, Fabian Pallasdies ... Sabine Begall
    Primate hand preference strength but not direction (left vs. right) generally reflects phylogeny and ecology at species level, but human handedness deviates markedly from all other species.
    1. Genetics and Genomics
    2. Stem Cells and Regenerative Medicine

    Highly efficient generation of isogenic pluripotent stem cell models using prime editing

    Hanqin Li, Oriol Busquets ... Frank Soldner
    A highly efficient platform to engineer designer mutations in human stem cells using RNA-based delivery of prime editing components.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Glycan-based shaping of the microbiota during primate evolution

    Sumnima Singh, Patricia Bastos-Amador ... Miguel P Soares
    Ggta1 deletion in mice shapes and reduces the microbiota pathogenicity and probably contributed to the natural selection of GGTA1 loss-of-function mutations in the ancestral primates that gave rise to humans.
    1. Neuroscience

    Preserved extrastriate visual network in a monkey with substantial, naturally occurring damage to primary visual cortex

    Holly Bridge, Andrew H Bell ... Kristine Krug
    Even when the primary visual cortical area is absent bilaterally from early life, the rest of a primate visual brain can develop and function normally to support day-to-day visual behaviour.
    1. Microbiology and Infectious Disease
    2. Genetics and Genomics

    Dissection of the in vitro developmental program of Hammondia hammondi reveals a link between stress sensitivity and life cycle flexibility in Toxoplasma gondii

    Sarah L Sokol, Abby S Primack ... Jon P Boyle
    A derived stress response trait may have contributed to the emergence of a globally dominant and promiscuous parasite.
    1. Neuroscience

    Population receptive fields in nonhuman primates from whole-brain fMRI and large-scale neurophysiology in visual cortex

    P Christiaan Klink, Xing Chen ... Pieter R Roelfsema
    Within-species comparison of population receptive fields determined with fMRI and electrophysiology in nonhuman primates reveals the neuronal basis of blood-oxygen-level-dependent-based retinotopy.
    1. Neuroscience

    Spatial signatures of anesthesia-induced burst-suppression differ between primates and rodents

    Nikoloz Sirmpilatze, Judith Mylius ... Susann Boretius
    Functional imaging (fMRI) across four mammalian species maps the brain areas engaging in burst-suppression activity during anesthesia, and uncovers differences between primates and rodents.
    1. Neuroscience

    Targeted cortical reorganization using optogenetics in non-human primates

    Azadeh Yazdan-Shahmorad, Daniel B Silversmith ... Philip N Sabes
    Focal optogenetic stimulation strengthens functional connectivity between primary somatosensory and motor cortices in macaques, in a manner consistent with a Hebbian model of stimulus-driven plasticity.
    1. Neuroscience

    Columnar processing of border ownership in primate visual cortex

    Tom P Franken, John H Reynolds
    The assignment of borders to foreground objects occurs in cortical columns in primate visual cortex, and first in deep layers, suggesting a central role for feedback.

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