The dynamic current generated Na⁺/K⁺ pump interacts with the h-current to control the bursting activity of oscillator heart interneurons.

Comparative neuroimaging quantifies the congruence of regional neuroanatomical sex differences between humans and mice.

Crystal structures provide structural rationales for the transport stoichiometry of the gastric proton pump, which suffices the energy requirement for the generation of a million-fold proton gradient across the membrane.

The tripartite drug efflux pump AcrA-AcrB-TolC, representative of a wide group of pumps from Gram-negative bacteria, enters a transport-competent state through long-distance conformational changes that switch the channel from a closed to an open state.

Short peptides that bind tightly to anti-apoptotic protein Bfl-1 but not other Bcl-2 family members provide a tool for diagnosing cancer cell survival mechanisms and a lead for developing new therapeutics.

The complex process of protein translocation across membranes has been dissected into multiple key steps and the distributions of translocation rates indicate stochastic nature of the reaction.

A newly identified microtubule binding activity of NuMA is required for orienting the mitotic spindle.

Belly roll, Bero, an Ly6/α-neurotoxin family protein, is identified as a critical modulator of peptidergic interneurons in Drosophila melanogaster, shedding light on genetic regulations of nociceptive escape behaviors and providing a potential target for future studies on pain perception.

Using bioinformatic and biochemical approaches, the study has explained the discriminator base anomaly in bacterial tRNA(Gly) through identification of the key determinant of DTD specificity.

Long noncoding RNA Norad performs an essential function in mammalian physiology by inhibiting the activity of PUMILIO RNA binding proteins, thereby suppressing a multi-system degenerative phenotype resembling premature aging.