A lipid-binding protein mediates both attraction and hypersensitivity to a beetle sex pheromone in a specific type of nematode-insect relationship known as necromeny.

A human three-helix Rab-binding domain can potentially bind to two Rab proteins simultaneously with different affinities at binding sites generated by gene duplication.

A laboratory experiment provides the first evidence that framing a sham treatment as personalised to one's genetics and physiology increases its placebo effect on pain.

Selective synapse formation in a retinal motion-sensitive circuit is orchestrated by starburst amacrine cells, which use homotypic interactions to initiate formation of a dendritic scaffold that recruits projections from circuit partners.

Despite relative impermeability of the blood-brain barrier for calcitonin gene-related peptide antibodies used in migraine treatment, these antibodies induce certain and highly specific brain effects particularly in the hypothalamus which may be part of the mechanism of their efficacy.

Genetic variations that underlie common autoimmune disease genes are predominantly regulatory and modify the expression of multiple genes within the HLA gene complex and throughout the immune system.

Analysis of the atypical tryptophan biosynthetic operon of Chlamydia trachomatis revealed the simultaneous regulation of transcriptional initiation and termination by an iron-dependent repressor, expanding known regulatory mechanisms of this pathway.

Identification of activity-dependent transcriptional changes in striatal neurons reveals a conserved functional enhancer for prodynorphin.

Inactivation of the Dictyostelium orthologue of the tumour suppressor Neurofibromin (NF1) enables amoebae to ingest dissolved nutrients using macropinocytosis more rapidly, and to prey on larger organisms using phagocytosis.

The existence of a slow-moving zone around the transcription site may unify conflicting models of co-transcriptional versus post-transcriptional mRNA splicing.