A model of hippocampal replay is proposed that gives a biologically plausible account of how the hippocampus could prioritize replay and produce a variety of different replay statistics, and is efficient in driving spatial learning.
Margot Tirole, Marta Huelin Gorriz ... Daniel Bendor
Hippocampal place cells modulate their firing rate during replay events to reflect the increases, or decreases, in firing rate experienced between contexts during behavior.
Replay of recently experienced trajectories during a decision task is coupled with more effective adaptation to change, whereas replay during rest is associated with limited decision making flexibility.
Tuned protein–protein interaction affinity optimizes the repressive function of the ETS family transcription factor Yan in order to contribute specificity and robustness to cell fate specification in the developing Drosophila eye.
fMRI evidence for off-task replay predicts subsequent replanning behavior in humans, suggesting that learning from simulated experience during replay helps update past policies in reinforcement learning.
Eric L Denovellis, Anna K Gillespie ... Loren M Frank
A new state space decoder revealed that most hippocampal sharp-wave ripples contain coherent spatial content, and that this 'replay' typically progresses at speeds similar to those seen during actual experiences.
Specific to muscles and essential for their development, desmin is revealed to be fundamental to the mechanics and shape maintenance of model muscle tissue even in early differentiating and unorganized systems through an integrated magnetic tensiometer approach.
Spontaneous, irregular spiking in single cortical pyramidal neurons assembles as neuronal avalanches at the group level identifying a robust scale-invariant organization of resting activity in the awake state.