15,473 results found
    1. Biochemistry and Chemical Biology

    Meta-Research: Task specialization across research careers

    Nicolas Robinson-Garcia, Rodrigo Costas ... Gabriela F Nane
    An analysis of author contribution statements in a large number of published papers reveals biases in the career trajectories of scientists.
    1. Developmental Biology
    2. Medicine

    Meta-Research: The need for more research into reproductive health and disease

    Natalie D Mercuri, Brian J Cox
    An analysis of publications and research grants shows that the volume of research on reproductive organs is much less than that on non-reproductive organs.
    1. Medicine

    Epidemiological characteristics and prevalence rates of research reproducibility across disciplines: A scoping review of articles published in 2018-2019

    Kelly D Cobey, Christophe A Fehlmann ... David Moher
    Definitions of reproducibility vary considerably across disciplines and overall rates of reproducibility are low irrespective of the definition used.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Meta-Research: COVID-19 research risks ignoring important host genes due to pre-established research patterns

    Thomas Stoeger, Luís A Nunes Amaral
    An analysis of 10,395 research publications about COVID-19 that mention at least one human gene reveals that many genes implicated in SARS-CoV-2 infection by genome-wide studies remain unstudied.
    1. Neuroscience

    Sniff-synchronized, gradient-guided olfactory search by freely moving mice

    Teresa M Findley, David G Wyrick ... Matthew C Smear
    To track odors borne on turbulent airflow, mice strategically follow their nose, with sampling movements and sensory computations reminiscent of those demonstrated in nematodes and insects.
  1. Research Culture: A survey of early-career researchers in Australia

    Katherine Christian, Carolyn Johnstone ... Michael R Doran
    Job insecurity is putting stress on early-career researchers in Australia, compromising their career development and potentially reducing the quality of research.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    National Institutes of Health research project grant inflation 1998 to 2021

    Michael S Lauer, Joy Wang, Deepshikha Roychowdhury
    National Institutes of Health (NIH) grants have evolved over time, with a greater proportion of funds going to solicited projects, but inflation-adjusted costs have remained relatively stable following a brief increase during the NIH-doubling (1998-2003).
    1. Medicine

    Meta-research: justifying career disruption in funding applications, a survey of Australian researchers

    Adrian Barnett, Katie Page ... Susanna Cramb
    A survey of health and medical researchers revealed important diffrences in how career disruption is treated in funding decisions, with differences in what applicants with disruption are willing to divulge and the adjustments made by reviewers.
    1. Computational and Systems Biology

    Sensitive remote homology search by local alignment of small positional embeddings from protein language models

    Sean R Johnson, Meghana Peshwa, Zhiyi Sun
    Protein language deep learning models can quickly and accurately translate amino acid sequences into profile hidden Markov models or a structure alphabet, dramatically improving remote homology search sensitivity without compromising space or time efficiency.
  2. Meta-Research: Questionable research practices may have little effect on replicability

    Rolf Ulrich, Jeff Miller
    Although questionable research practices inflate false positive rates, they have little effect on replicability because they also increase power.

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