487 results found
    1. Ecology
    2. Physics of Living Systems

    Multiplexed microfluidic screening of bacterial chemotaxis

    Michael R Stehnach, Richard J Henshaw ... Jeffrey S Guasto
    A multiplexed microfluidic device was developed to facilitate high-throughput screening of bacterial chemotaxis on a single chip and demonstrated across a range of microbes, chemostimulants, and chemical gradient conditions.
    1. Physics of Living Systems

    Hydrodynamic model of fish orientation in a channel flow

    Maurizio Porfiri, Peng Zhang, Sean D Peterson
    A hydrodynamic model of fish swimming in a channel predicts a critical flow speed for fish to successfully swim against a flow, unveiling a passive mechanism for rheotaxis to emerge without access to any sensory information.
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    CryoEM and computer simulations reveal a novel kinase conformational switch in bacterial chemotaxis signaling

    C Keith Cassidy, Benjamin A Himes ... Peijun Zhang
    An atomic model of the bacterial chemosensory array obtained through the synthesis of cryo-electron tomography and large-scale molecular-dynamics simulations reveals a new kinase conformation during signaling events.
    1. Genetics and Genomics
    2. Neuroscience

    Roles of the ClC chloride channel CLH-1 in food-associated salt chemotaxis behavior of C. elegans

    Chanhyun Park, Yuki Sakurai ... Hirofumi Kunitomo
    A ClC chloride channel protein allows neurons to interpret both temporal resolution and intensity of sensory input, which thereby contributes to an experience-dependent navigation behavior.
    1. Physics of Living Systems

    Sperm chemotaxis is driven by the slope of the chemoattractant concentration field

    Héctor Vicente Ramírez-Gómez, Vilma Jimenez Sabinina ... Adán Guerrero
    The slope of the chemoattractant concentration gradient is a driving force for sperm chemotaxis, by coordinating the entrainment of information flow between sensing, signaling and motility.
    1. Physics of Living Systems

    Asymmetric random walks reveal that the chemotaxis network modulates flagellar rotational bias in Helicobacter pylori

    Jyot D Antani, Anita X Sumali ... Pushkar P Lele
    Asymmetric forward and backward swimming speeds reveal that the rotational bias, and not reversal frequencies, is an appropriate measure of chemotaxis signaling in Helicobacter pylori..
    1. Physics of Living Systems

    Rheotaxis facilitates upstream navigation of mammalian sperm cells

    Vasily Kantsler, Jörn Dunkel ... Raymond E Goldstein
    Mammalian sperm subject to shear flow swim in upstream spirals along the walls bounding such flows, thereby demonstrating a robust mechanism for upstream navigation to the ovum.
    1. Cell Biology
    2. Immunology and Inflammation

    Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo

    Asif J Iqbal, Tessa J Barrett ... Edward A Fisher
    Mechanistic insights show how treatment with apoA1 is anti-inflammatory by rapidly disrupting macrophage chemotaxis and monocyte recruitment.
    1. Neuroscience

    Sensorimotor pathway controlling stopping behavior during chemotaxis in the Drosophila melanogaster larva

    Ibrahim Tastekin, Avinash Khandelwal ... Matthieu Louis
    The reconstruction of a sensorimotor pathway from the olfactory-sensory neurons down to the pre-motor system reveals a descending neuron that plays a critical role in the organization of larval chemotaxis.
    1. Cell Biology

    ERK3/MAPK6 controls IL-8 production and chemotaxis

    Katarzyna Bogucka, Malvika Pompaiah ... Krishnaraj Rajalingam
    Understudied atypical MAPK, ERK3 controls epithelial secretome and chemotaxis.

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