356 results found
    1. Ecology
    2. Evolutionary Biology
    Silhouette of a rhesus macaque on a yellow/orange background.

    The Natural History of Model Organisms: The rhesus macaque as a success story of the Anthropocene

    Eve B Cooper, Lauren JN Brent ... James P Higham
    The rhesus macaque is a non-human primate that is widely used as a model organism in ecology, evolutionary biology and behavioural science.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch

    Zijun Wang, Christopher O Barnes ... Amelia Escolano
    Rhesus macaques can develop broadly neutralizing antibodies (bNAbs) against the V3-glycan patch of Env that resembles human V3/N332 bNABs.
    1. Neuroscience

    A novel rhesus macaque model of Huntington’s disease recapitulates key neuropathological changes along with motor and cognitive decline

    Alison R Weiss, William A Liguore ... Jodi L McBride
    mHTT delivery in key cortical and subcortical brain regions leads to hallmark mHTT aggregate formation, gray and white matter degenerative changes, along with motor and cognitive decline in a new macaque model of Huntington's disease.
    1. Evolutionary Biology
    2. Neuroscience

    Connectional asymmetry of the inferior parietal lobule shapes hemispheric specialization in humans, chimpanzees, and rhesus macaques

    Luqi Cheng, Yuanchao Zhang ... Tianzi Jiang
    Humans showed the most widespread asymmetric connectivity between the inferior parietal lobule subregions and the rest of the brain compared to macaques and chimpanzees, which shapes hemispheric specialization in primates.
    1. Immunology and Inflammation

    Tailoring Tfh profiles enhances antibody persistence to a clade C HIV-1 vaccine in rhesus macaques

    Anil Verma, Chase E Hawes ... Smita S Iyer
    Strategies to enhance Tfh cells for HIV-vaccine antibody persistence and protection is pivotal for vaccine success.
    1. Neuroscience

    Intrinsic timescales as an organizational principle of neural processing across the whole rhesus macaque brain

    Ana MG Manea, Anna Zilverstand ... Jan Zimmermann
    Neuroimaging proves to be a powerful tool for capturing spatial and temporal dynamics across the whole nonhuman primate brain, bridging the gap between human and animal models.
    1. Developmental Biology
    2. Neuroscience

    Temporal transcriptomic dynamics in developing macaque neocortex

    Longjiang Xu, Zan Yuan ... Xiaozhong Peng
    A useful single-cell resource provides the prenatal macaque different cell types’ gene expression profiles in the parietal cerebral cortex lobe.
    1. Neuroscience

    Human and macaque pairs employ different coordination strategies in a transparent decision game

    Sebastian Moeller, Anton M Unakafov ... Igor Kagan
    Using novel approach to study real-time social interactions shows that mutual action visibility facilitates static and dynamic coordination in both species, but whereas humans employ dynamic turn-taking to equalize rewards, macaques, after training with a human, compete between themselves.
    1. Ecology

    Higher social tolerance is associated with more complex facial behavior in macaques

    Alan V Rincon, Bridget M Waller ... Jérôme Micheletta
    Detailed quantification of macaque facial behavior reveals a positive link between social and communicative complexity, and helps us to better understand the evolution of animal communication.
    1. Neuroscience

    Preserved extrastriate visual network in a monkey with substantial, naturally occurring damage to primary visual cortex

    Holly Bridge, Andrew H Bell ... Kristine Krug
    Even when the primary visual cortical area is absent bilaterally from early life, the rest of a primate visual brain can develop and function normally to support day-to-day visual behaviour.

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