63 results found
    1. Plant Biology

    Pathogen effectors and plant immunity determine specialization of the blast fungus to rice subspecies

    Jingjing Liao, Huichuan Huang ... Jean-Benoit Morel
    Specialized fungal pathogen populations infect rice varieties with contrasting immune systems co-cultivated in a traditional agro-system, indicating the relevance of crop diversity to restricting epidemics in the landscape.
    1. Structural Biology and Molecular Biophysics
    2. Plant Biology

    Structural basis of pathogen recognition by an integrated HMA domain in a plant NLR immune receptor

    A Maqbool, H Saitoh ... MJ Banfield
    Structure/function studies of a plant pathogen effector in complex with a host disease resistance protein domain reveal the molecular basis for recognition and underpin future engineering of immunity in crops.
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Protein engineering expands the effector recognition profile of a rice NLR immune receptor

    Juan Carlos De la Concepcion, Marina Franceschetti ... Mark J Banfield
    Structure-led protein engineering can expand the effector recognition profile of plant intracellular NLR immune receptors, providing a proof-of-principle for the development of novel disease resistance mechanisms in plants.
    1. Plant Biology

    Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor

    Josephine HR Maidment, Motoki Shimizu ... Mark J Banfield
    Effector target-guided engineering has developed plant NLR immune receptors that bind and recognize stealthy pathogen effector proteins, demonstrating new disease resistance profiles in planta, and offering a promising approach to protect crops against plant pathogens.
    1. Ecology

    Harbouring public good mutants within a pathogen population can increase both fitness and virulence

    Richard J Lindsay, Michael J Kershaw ... Ivana Gudelj
    Cooperation theory and a novel synthetic infection system provides a mechanistic understanding of why a seemingly successful disease management strategy can have devastating consequences for infected hosts.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A self-balancing circuit centered on MoOsm1 kinase governs adaptive responses to host-derived ROS in Magnaporthe oryzae

    Xinyu Liu, Qikun Zhou ... Zhengguang Zhang
    A phosphorylation circuitry balancing among kinase, transcription factor, transcription repressor, and phosphatase in response against host immunity during M. oryzae–rice interaction.
    1. Microbiology and Infectious Disease

    Exosomes mediate horizontal transmission of viral pathogens from insect vectors to plant phloem

    Qian Chen, Yuyan Liu ... Taiyun Wei
    An important rice reovirus hijacks exosomes to traverse the apical plasmalemma into saliva-stored cavities in the salivary glands of insect vectors, facilitating viral horizontal transmission into rice phloem.
    1. Microbiology and Infectious Disease

    Genome editing of an African elite rice variety confers resistance against endemic and emerging Xanthomonas oryzae pv. oryzae strains

    Van Schepler-Luu, Coline Sciallano ... Wolf B Frommer
    Discovery of a rapidly spreading outbreak of bacterial blight in Tanzania caused by a Xanthomonas strain that originates from Asia and editing of Komboka rice lines resistant to the newly introduced strains and to other Asian and African strains.
    1. Plant Biology

    An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

    Hiroaki Adachi, Mauricio P Contreras ... Sophien Kamoun
    The MADA motif is functionally conserved across NLRs from distantly related plants and has degenerated in sensor NLRs over evolutionary time.
    1. Plant Biology

    Two NLR immune receptors acquired high-affinity binding to a fungal effector through convergent evolution of their integrated domain

    Aleksandra Białas, Thorsten Langner ... Sophien Kamoun
    The HMA domains of Pikp-1 and Pikm-1 NLR receptors have convergently evolved to bind AVR-PikD with high affinity through distinct evolutionary and biochemical paths.

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