A shift in antero-posterior positional information may contribute to the fin-to-limb transformation.

Linking deep mutational scanning with engineered transcriptional reporters in human cell lines establishes a generalizable method for exploring pharmacogenomics, structure, and function across broad classes of drug receptors.

The development of diverse tooth shapes among vertebrates, from sharks to mammals, is a highly conserved process, utilising a similar dental signalling centre for more than 400 million years.

Deficiency of capicua, a transcription factor that suppresses autoimmunity, impairs positive and negative selection processes by attenuating TCR signaling in CD4⁺CD8⁺ double-positive thymocytes.

A novel micropositioning approach allows remote-controlled, micrometer-resolution actuation of many densely packed, arbitrarily shaped probes with a device whose size and weight scale much more efficiently with probe count compared to current methods.

Dynamic calcium activity in the hippocampus changes markedly across behavioral and physiological states and depends on muscarinic acetylcholine receptor activation.

A novel technology for recording muscle activity provides unprecedented access to the electrical signals that control the body across muscles, species, and behaviors.

The medial and lateral subdivisions of the entorhinal cortex are important for deciding "where to go from here" and "what to do to this object" in a visual context, respectively.

Blocking input from basolateral amygdala to gustatory cortex (GC) severely reduces the coherence of GC ensemble activity, which negatively affects epochal dynamics involved in driving palatability-driven consumption.

Astrocytic G_i pathway activation in the anterior cingulate cortex impairs schema memory and neuronal mitochondrial biogenesis, which can be rescued by exogenous L-lactate administration directly into the area.