4,332 results found
    1. Ecology
    2. Neuroscience

    Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase

    Sven Schenk, Stephanie C Bannister ... Kristin Tessmar-Raible
    A molecular profiling approach to quantify transcripts and proteins from identical samples allows study of molecular effects of maturation, sexual differentiation and the endogenous circalunar clock in a marine worm.
    1. Neuroscience

    Schema representations in distinct brain networks support narrative memory during encoding and retrieval

    Rolando Masís-Obando, Kenneth A Norman, Christopher Baldassano
    Neural representations of both general event schemas and story-specific details predict memory performance in narrative recall, with distinct brain networks tracking schematic information during perception versus retrieval.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

    Matthew J Shurtleff, Morayma M Temoche-Diaz ... Randy Schekman
    A cell-free reaction that reconstitutes the selective sorting of a miRNA into exosomes reveals an RNA-binding protein, YBX1, as a critical sorting factor.
    1. Neuroscience

    A Mammalian enhancer trap resource for discovering and manipulating neuronal cell types

    Yasuyuki Shima, Ken Sugino ... Sacha B Nelson
    A novel transposon-based enhancer trap screen in mice permits high throughput development of highly restricted driver strains targeting specific neuronal cell types.
    1. Genetics and Genomics
    2. Neuroscience

    Sensory neurons couple arousal and foraging decisions in Caenorhabditis elegans

    Elias Scheer, Cornelia I Bargmann
    A long-term arousal state is linked to the acute decision to leave a food patch by sensory neurons that integrate neuromodulatory information, food intake, and environmental signals.
    1. Ecology
    2. Plant Biology

    Plant defense phenotypes determine the consequences of volatile emission for individuals and neighbors

    Meredith C Schuman, Silke Allmann, Ian T Baldwin
    Both the frequency of sesquiterpene-emitting individuals and the defense capacity of individual plants determine the consequences of sesquiterpene volatile emission for individuals and their neighbors in populations of the wild tobacco Nicotiana attenuata.
    1. Cell Biology
    2. Neuroscience

    Large-scale cell-type-specific imaging of protein synthesis in a vertebrate brain

    Or David Shahar, Erin Margaret Schuman
    The development of a transgenic zebrafish allows for cell-type-specific labeling of neuronal protein synthesis, enabling brain-wide visualization and quantification of protein synthesis and demonstrating region-specific increases following elevated brain activity.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

    Morayma M Temoche-Diaz, Matthew J Shurtleff ... Randy Schekman
    Biochemical fractionation of vesicle sub-populations and in vitro reconstitution studies reveal that Lupus La protein mediates the selective sorting of miR-122 into extracellular vesicles in vitro and in vivo.
    1. Plant Biology
    2. Evolutionary Biology

    Herbivory-induced volatiles function as defenses increasing fitness of the native plant Nicotiana attenuata in nature

    Meredith C Schuman, Kathleen Barthel, Ian T Baldwin
    A 2-year field study has demonstrated that volatile compounds produced by plants when they are attacked by herbivores act as defenses by attracting predators to the herbivores and increasing the reproduction of the plants.
    1. Neuroscience

    Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons

    Julio D Perez, Susanne tom Dieck ... Erin M Schuman
    Single somata and dendrites of individual rat neurons were laser-captured and sequenced to discover and compare the subcellular transcriptomes, identifying over 4000 mRNAs in GABAergic dendrites.

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