6,675 results found
    1. Epidemiology and Global Health

    Nationwide mammography screening participation in Denmark during the COVID-19 pandemic: An observational study

    Tina Bech Olesen, Henry Jensen ... Sisse H Njor
    Only a minor reduction in mammography screening participation was observed during the COVID-19 pandemic in Denmark.
  1. Meta-Research: Questionable research practices may have little effect on replicability

    Rolf Ulrich, Jeff Miller
    Although questionable research practices inflate false positive rates, they have little effect on replicability because they also increase power.
    1. Epidemiology and Global Health
    2. Medicine

    A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean

    Rodrigo M Carrillo-Larco, C Joel Benites-Moya ... Antonio Bernabe-Ortiz
    In Latin America and the Caribbean the most common dyslipidaemia seems to be low HDL-cholesterol, and there has been little change in time for both mean levels and prevalence estimates.
  2. Point of View: Overflow in science and its implications for trust

    Sabina Siebert, Laura M. Machesky, Robert H. Insall
    Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link

    Huyen Nguyen, Christian Wandell Thorball ... The Swiss HIV Cohort Study
    The presence of certain HLA alleles drives the emergence or maintenance of otherwise deleterious drug-resistant mutations in patients living with HIV, even when the patient is antiretroviral treatment naïve.
    1. Medicine

    Science Forum: Improving preclinical studies through replications

    Natascha Ingrid Drude, Lorena Martinez Gamboa ... Ulf Toelch
    Increasing validity should be a priority when deciding which preclinical experiments to replicate and when performing replications.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging

    John Darby Cole, Jacobo Sarabia del Castillo ... Sebastian Jessberger
    Iterative immunostaining using 4i enables detailed characterization of complex mouse and human tissues.
  3. Research Culture: A survey-based analysis of the academic job market

    Jason D Fernandes, Sarvenaz Sarabipour ... Amanda Haage
    A survey of over 300 applicants for faculty positions reveals that there are many paths to securing a job offer.
  4. Science Forum: Sex differences and sex bias in human circadian and sleep physiology research

    Manuel Spitschan, Nayantara Santhi ... Rhiannon White
    Research on human sleep and circadian physiology exhibits a bias towards male subjects, creating a sex data gap which holds potential real-world impact and requires concerted effort to close.
  5. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.

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