16,458 results found
    1. Microbiology and Infectious Disease

    Evolutionary consequences of intra-patient phage predation on microbial populations

    Kimberley D Seed, Minmin Yen ... Andrew Camilli
    Bacterial viruses are an unexpected ‘third party’ that imposes a strong predatory pressure on a bacterial pathogen during the natural course of infection in humans.
    1. Microbiology and Infectious Disease

    A chimeric nuclease substitutes a phage CRISPR-Cas system to provide sequence-specific immunity against subviral parasites

    Zachary K Barth, Maria HT Nguyen, Kimberley D Seed
    Horizontal transfer of a sequence-specific DNA-binding domain allows a virus to destroy its subviral parasite and overcome parasite-mediated restriction.
    1. Neuroscience

    Paranoia as a deficit in non-social belief updating

    Erin J Reed, Stefan Uddenberg ... Philip R Corlett
    Paranoia is underwritten by variation in prior beliefs about how the world will change and how to learn from those changes.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Hydrodynamics of sponge pumps and evolution of the sponge body plan

    Seyed Saeed Asadzadeh, Thomas Kiørboe ... Jens H Walther
    The architecture of flagellated chambers in sponge pumps is linked to that of body plan, supporting the current view that the sponge aquiferous system evolved from an open-type filtration system.
    1. Computational and Systems Biology
    2. Neuroscience

    Automated analysis of long-term grooming behavior in Drosophila using a k-nearest neighbors classifier

    Bing Qiao, Chiyuan Li ... Sheyum Syed
    Drosophila grooming is driven by two internal programs.
    1. Microbiology and Infectious Disease

    Dominant Vibrio cholerae phage exhibits lysis inhibition sensitive to disruption by a defensive phage satellite

    Stephanie G Hays, Kimberley D Seed
    Genetic and molecular analyses identify and characterize an evolutionary battle over lysis timing wherein a bacteriophage delays lysis through lysis inhibition while a defensive phage satellite accelerates lysis.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

    Caroline M Boyd, Sundharraman Subramanian ... Kimberley D Seed
    A phage parasite encodes an external scaffolding protein to pirate and rearrange phage-encoded coat proteins to more efficiently transfer the phage parasite genome to new hosts and limit phage production.
    1. Neuroscience

    Coordinated neuronal ensembles in primary auditory cortical columns

    Jermyn Z See, Craig A Atencio ... Christoph E Schreiner
    Auditory cortical columns contain small subsets of neurons with highly synchronous activity (cNEs) that create robust sequences of coordinated activity suitable for enhanced information processing and signal transmission beyond the capability of individual neurons.
    1. Plant Biology

    Auxin production in the endosperm drives seed coat development in Arabidopsis

    Duarte D Figueiredo, Rita A Batista ... Claudia Köhler
    Auxin is produced in the endosperm after fertilization and drives the development of the seed coat in Arabidopsis.
    1. Neuroscience

    Simultaneous activation of parallel sensory pathways promotes a grooming sequence in Drosophila

    Stefanie Hampel, Claire E McKellar ... Andrew M Seeds
    A grooming sequence is produced by a neural architecture that readies different movements simultaneously, and a mechanism where prioritized suppression between the movements determines their sequential performance.

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