328 results found
    1. Cell Biology
    2. Developmental Biology

    Distribution of neurosensory progenitor pools during inner ear morphogenesis unveiled by cell lineage reconstruction

    Sylvia Dyballa, Thierry Savy ... Cristina Pujades
    The first dynamic map of early neuronal and sensory progenitors in the whole otic vesicle reveals how progenitor domains remodel upon morphogenesis.
    1. Developmental Biology
    2. Neuroscience

    Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

    Sung-Ho Huh, Mark E Warchol, David M Ornitz
    Otic epithelial Fibroblast Growth Factors control the number of cochlear sensory progenitor cells through an FGF responsive periotic mesenchyme.
    1. Developmental Biology
    2. Genetics and Genomics

    Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris

    Brent A Wilkerson, Heather L Zebroski ... Olivia Bermingham-McDonogh
    The elucidation of the cellular composition of the crista and the genes expressed in each cell type is a critical step toward understanding inner ear development, function, and vestibulopathies.
    1. Developmental Biology
    2. Neuroscience

    Movement maintains forebrain neurogenesis via peripheral neural feedback in larval zebrafish

    Zachary Jonas Hall, Vincent Tropepe
    Early postembryonic bodily movement sends neural feedback through dorsal root ganglia to the forebrain in order to regulate the rate of neurogenesis and subsequent brain growth.
    1. Developmental Biology
    2. Neuroscience

    Lineage does not regulate the sensory synaptic input of projection neurons in the mouse olfactory bulb

    Luis Sánchez-Guardado, Carlos Lois
    Sister projection neurons in the mammalian olfactory system do not share sensory synaptic input indicating that lineage-independent mechanisms regulate their synaptic connectivity with the olfactory sensory neurons.
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    1. Developmental Biology
    2. Neuroscience

    Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes

    Tuo Shi, Marielle O Beaulieu ... David W Raible
    Single-cell transcriptomic analysis defines hair cell and supporting cell types in the zebrafish inner ear, and reveals homologies with cells in the mammalian ear.
    1. Cell Biology
    2. Developmental Biology

    A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology

    Jérôme Lacoste, Hédi Soula ... Sophie Louvet-Vallée
    Timing of neural precursor cells division controls the order of development of sensory neurons, which in turn determines their axon terminal pattern and ultimately fly behaviour.
    1. Cell Biology
    2. Neuroscience

    Long-range migration of centrioles to the apical surface of the olfactory epithelium

    Kaitlin Ching, Jennifer T Wang, Tim Stearns
    Olfactory sensory neurons have centrioles that are amplified in number and that migrate from the cell body to the end of the dendrite relatively slowly and in groups, becoming mature only after they reach their destination.
    1. Stem Cells and Regenerative Medicine

    ErbB expressing Schwann cells control lateral line progenitor cells via non-cell-autonomous regulation of Wnt/β-catenin

    Mark E Lush, Tatjana Piotrowski
    Schwann cell induced quiescence of mechanosensory progenitor cells is mediated by inhibition of Wnt/β-catenin signaling.
    1. Developmental Biology
    2. Neuroscience

    Molecular characterization of cell types in the squid Loligo vulgaris

    Jules Duruz, Marta Sprecher ... Simon G Sprecher
    Single-cell transcriptomics correlated with in situ gene expression analysis provide an overview of the diversity and molecular features of cell types in the squid Loligo vulgaris.

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