10,535 results found
    1. Cell Biology

    Telocytes regulate macrophages in periodontal disease

    Jing Zhao, Anahid A Birjandi ... Paul Sharpe
    A poorly understood cell type, the telocyte, is shown to regulate macrophages.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease

    Ana J Caetano, Val Yianni ... Paul Sharpe
    Single cell transcriptomic analysis provides a reference map for human oral muscosa in health and disease and a framework for the development of new therapeutic strategies.
    1. Developmental Biology

    Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis

    Neus Martínez-Abadías, Roger Mateu Estivill ... James Sharpe
    Quantitative analyses associating the morphology of developing organs with dynamic gene expression patterns can reveal biological phenomena that cause malformations and malfunction but remain elusive to traditional qualitative assessments.
    1. Neuroscience

    Nucleus reuniens of the thalamus contains head direction cells

    Maciej M Jankowski, Md Nurul Islam ... Shane M O'Mara
    Neurons that provide information about the direction of the head are present in nucleus reuniens and can potentially directly influence spatial processing in the hippocampus.
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    1. Neuroscience

    Perception of an object’s global shape is best described by a model of skeletal structure in human infants

    Vladislav Ayzenberg, Stella Lourenco
    Six- to twelve-month old infants, who have little linguistic or object experience, classify objects by relying on a invariant representation of global shape known as the shape skeleton.
    1. Neuroscience

    The large-scale organization of shape processing in the ventral and dorsal pathways

    Erez Freud, Jody C Culham ... Marlene Behrmann
    Functional neuroimaging reveals sensitivity to shape information and correlation between brain activation and perceptual behaviour in both dorsal and ventral visual pathways, thereby challenging the strict binary distinctions between the two pathways.
    1. Developmental Biology
    2. Physics of Living Systems

    On the origin of universal cell shape variability in confluent epithelial monolayers

    Souvik Sadhukhan, Saroj Kumar Nandi
    The nearly universal nature of scaled cell shape variability in an epithelial monolayer is unavoidable, irrespective of health or disease, as it comes from a mathematical property.
    1. Neuroscience
    2. Computational and Systems Biology

    The individuality of shape asymmetries of the human cerebral cortex

    Yu-Chi Chen, Aurina Arnatkevičiūtė ... Kevin M Aquino
    Asymmetries between the shape of the left and right human cortex are highly unique to individuals, akin to a neuroanatomical fingerprint, related to cognitive function, and primarily driven by person-specific environmental influences.
    1. Computational and Systems Biology
    2. Developmental Biology

    Why plants make puzzle cells, and how their shape emerges

    Aleksandra Sapala, Adam Runions ... Richard S Smith
    Puzzle-shape cells in the epidermis of many plants form due to a development constraint based on mechanical forces.
    1. Cell Biology

    Scaling of subcellular actin structures with cell length through decelerated growth

    Shane G McInally, Jane Kondev, Bruce L Goode
    The size of a subcellular structure, yeast actin cables, scales with the linear dimensions of the cell, which is achieved by feedback control of their growth rate.
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