Reetu Daswani, Carlotta Gilardi ... Gerhard Schratt
A new molecular mechanism involving microRNA, which controls synaptic transmission in a specialized type of inhibitory interneurons in the hippocampus and short-term memory in mice, was identified.
A fundamental lower-bound on memory recall precision, which declines with storage duration and number of stored items, is derived, and human performance is shown to be well-fit by this theoretical bound.
Paul Pfeiffer, Alexei V Egorov ... Susanne Schreiber
Independently gating ion channels typically act fast within milliseconds, but cooperative interactions within a cluster of channels allow for a memory of previous electrical activity for several seconds.
Dopamine and GABA neurons in the ventral tegmental area encode short-term memory in the T-maze task, which cannot be explained by reward-related processes, motivated behavior, or motor-related activities.
Seemingly disparate working memory biases, including short-term serial and contraction biases, may arise from a common mechanism via the interaction of multiple networks, each operating over a distinct timescale.
Intense starvation with high internal energy levels results in remarkably stable food-related memories that persist beyond actual food intake and are associated with overeating.
Thi-Minh Nguyen, Dietmar Schreiner ... Peter Scheiffele
Interneuron-specific alternative splice variants of the synaptic receptor neurexin are critical for hippocampal network activity and short-term memory.
A recurrent reward circuit in Drosophila, comprised of specific dopamine neurons and a single class of mushroom body output neurons, transforms a nascent memory trace into a stable long-term memory.