24 results found
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere

    Kitty F Verzijlbergen, Olga O Nerusheva ... Adele L Marston
    Shugoshin proteins help to align chromosomes so that copies of the same chromosome attach to microtubules from opposite poles during cell division.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes

    Ahmed Rattani, Magda Wolna ... Kim Nasmyth
    Shugoshin-like protein 2 (Sgol2) is involved in a variety of cell cycle process during the first stage of meiotic division.
    1. Chromosomes and Gene Expression

    Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis

    Candice L Wike, Hillary K Graves ... Jessica K Tyler
    A histone modification that alters the nucleosome structure occurs in mitosis and promotes chromosome packaging and the timely removal of condensin I and cohesion, to achieve chromosome segregation.
    1. Cell Biology

    BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes

    Laura Bel Borja, Flavie Soubigou ... Federico Pelisch
    BUB-1 recruits PP2A/B56 to regulate chromosome congression in meiosis I.
    1. Cell Biology

    Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524

    Anna P Baron, Conrad von Schubert ... Erich A Nigg
    Chemical inhibition of Bub1 shows that the catalytic activity is not required for normal mitotic progression, but it makes chromosome segregation and cell proliferation more sensitive to the effects of the anti-cancer drug Paclitaxel.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

    Saravanapriah Nadarajan, Firaz Mohideen ... Monica P Colaiacovo
    Coordination between crossover designation and synaptonemal complex disassembly is executed via a conserved MAP kinase pathway and is critical for accurate chromosome segregation during meiosis.
    1. Chromosomes and Gene Expression

    Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail

    Brandon R Lowe, Rajesh K Yadav ... Janet F Partridge
    H3-G34R, V, and W oncohistonesin fission yeast cause differential K36 modification, DNA damage sensitivity and genome stability outcomes, highlighting the need for a thorough evaluation of distinct mutations.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL

    Gordana Wutz, Rene Ladurner ... Jan-Michael Peters
    CTCF protects cohesinSTAG1 from WAPL.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

    Agata P Zielinska, Zuzana Holubcova ... Melina Schuh
    Multiple age-related changes in chromosome architecture could explain why human oocyte aneuploidy increases with advanced maternal age.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes

    Aaron F Severson, Barbara J Meyer
    Mechanisms that tether and release replicated sister chromatids to produce sperm and eggs rely extensively on meiotic cohesin complexes that are endowed with unexpectedly different properties specified by a single interchangeable subunit, the α-kleisin.

Refine your results by:

Type
Research categories